Korean J Gastroenterol.  2008 Nov;52(5):293-297.

Clinicopathologic Characteristics of Adenocarcinoma in Cardia according to Siewert Classification

• Yoon HY
• Kim HI
• Kim CB

Abstract

BACKGROUND/AIMS: The aim of this study was to evaluate clinicopathologic differences between Type II and Type III groups that were classified by Siewert in cardia cancer.
METHODS
A hundred forty-one patients who were diagnosed as gastric cardia cancer and underwent surgery between January 1990 and December 2006 by single surgeon at Department of Surgery, Yonsei University College of Medicine were included in this study. The Kaplan-Meier method and log rank test were used for survival analysis.
RESULTS
Barrett's adenocarcinoma was recognized in two patients so called type I. There were significant differences between type II and III in aspect of depth of invasion, Lauren's classification, and the number of retrieved lymph nodes in which cancer infiltrated. In type III, prognostic factors affecting survival were depth of invasion and nodal status in contrast to the no demonstrable prognostic factors existing in type II. However, there were no differences in recurrence and survival between two groups. CONCULSIONS: Several clinicopathologic differences exist between type II and III cardia cancer. In the future, further evaluation is needed regarding the classification and entities of the cardia cancer.

Keyword

Siewert's classification; Cardia; Adenocarcinoma

MeSH Terms

Adenocarcinoma/classification/mortality/*pathology
Adolescent
Adult
Aged
Aged, 80 and over
Barrett Esophagus/pathology/surgery
*Cardia
Esophageal Neoplasms/classification/mortality/pathology
Female
Humans
Kaplan-Meiers Estimate
Lymphatic Metastasis
Male
Middle Aged
Neoplasm Staging
Prognosis
Stomach Neoplasms/classification/mortality/*pathology
Survival Analysis