Korean J Intern Med.
2001 Dec;16(4):277-280.
A Case of Mediastinal Angiomyolipoma
- Affiliations
-
- 1Departments of Internal Medicine, Dankook University Medical Center, Chonan, Korea.
- 2Departments of Pathology, Dankook University Medical Center, Chonan, Korea.
- 3Departments of Radiology, Dankook University Medical Center, Chonan, Korea.
Abstract
- Angiomyolipoma is a common tumor of the kidney but has rarely been found in the mediastinum. We report a case of angiomyolipoma of the posterior mediastinum in a 62-year-old woman. She experienced exertional dyspnea and intermittent cough at admission. Computed tomography indicated a tumor located at the left paravertebral and upper posterior mediastinum and MRI imaging demonstrated a mass with low signal intensity in T1-weighted image at T4-5 level. Thoracotomy was done for surgical removal of the tumor and histologic examination revealed a mesenchymal tumor composed of mature fat, capillaries and smooth muscle fibers. The tumor was immunohistochemically positive for CD34 and factor-VIII (for vascular component) smooth muscle actin (for smooth muscle component) and S-100 protein (for fat component). There have been four case reports about mediastinal angiomyolipoma, namely three Japanese cases and one French case. It is suggested that angiomyolipoma could be considered for the differential diagnosis of mediastinal tumors.
