Korean J Intern Med.  2001 Mar;16(1):40-43.

A Case of Malignant Proliferating Trichilemmoma of the Scalp with Multiple Metastases

Affiliations
  • 1Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
  • 2Department of Clinical Pathology, Soonchunhyang University College of Medicine, Seoul, Korea.

Abstract

We report a case of malignant proliferating trichilemmal tumor showing multiple distant metastases. The patient demonstrated a round mass in the right occipital area for 12 months and the lesion grew rapidly to assume 8x6.5x4cm in diameter, with areas of superficial erosion and crusting within the recent 3 months. The entire lesion was removed with a wide surgical excision. It recurred on the neck area 4 months after excision and the lesion was removed with surgical resection again. There was evidence of multiple metastases on CNS and mediastinal lymph nodes after 6 months. The patient was treated with cisplatin and etoposide combination chemotherapy and a partial response was achieved.

Keyword

Skin neoplasms; Scalp; Metastasis; Drug therapy

MeSH Terms

Adult
Antineoplastic Agents, Combined/administration & dosage
Biopsy, Needle
Brain Neoplasms/therapy
Brain Neoplasms/secondary*
Brain Neoplasms/pathology
Case Report
Combined Modality Therapy
Follow-Up Studies
Head and Neck Neoplasms/therapy
Head and Neck Neoplasms/surgery
Head and Neck Neoplasms/pathology*
Human
Immunohistochemistry
Lymphatic Metastasis
Male
Neoplasms, Basal Cell/therapy
Neoplasms, Basal Cell/secondary*
Neurosurgical Procedures/methods
Reoperation
Scalp*
Skin Neoplasms/therapy
Skin Neoplasms/surgery
Skin Neoplasms/pathology*
Tomography, X-Ray Computed
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