Yonsei Med J.  2000 Jun;41(3):426-429. 10.3349/ymj.2000.41.3.426.

Islet cell hyperplasia of the pancreas presenting as hyperinsulinemic hypoglycemia in an adult

• Kim YW
• Park YK
• Park JH
• Lee SM
• Lee J
• Ko SW
• Yang MH

• KMID: 711771
• DOI: http://doi.org/10.3349/ymj.2000.41.3.426

Abstract

A 72-year-old man who had suffered several episodes of syncope was diagnosed as having hyperinsulinemic hypoglycemia. Although imaging studies and percutaneous transhepatic portal venous sampling did not reveal the existence of any tumors in the pancreas, distal pancreatectomy was performed because the possibility of a small pancreatic endocrine tumor could not be completely rejected. External examination of the surgically removed pancreas did not reveal any tumors. Microscopically, the pancreas exhibited diffuse islet cell hyperplasia without nesidioblastosis. The patient remains euglycemic and has tolerated 24-hour fasting without any medication for a period of 10 months after the operation.

Keyword

Islet cell hyperplasia; hyperinsulinemic hypoglycemia; pancreas; adult

MeSH Terms

Aged
Case Report
Human
Hyperinsulinemia/etiology*
Hyperplasia
Hypoglycemia/etiology*
Islets of Langerhans/surgery
Islets of Langerhans/pathology*
Male
Pancreatectomy/methods
Treatment Outcome