J Korean Soc Endocrinol.  1997 Sep;12(3):485-492.

Nesidioblastosis in an Elderly Patient with Hyperinsulinemic Hypoglycemia

• Seo YK
• Nam JH
• Sin BH
• Kim JG
• Ha SW
• Kim BW
• Jung SW
• Yun YG
• Seo IS
• Cho CH

Abstract

Nesidioblastosis is characterized by a diffuse proliferation of islet cells arising from pancreatic ducts and is the most common cause of hyperinsulinemic hypoglycemia in newborns and infantile. It is exceedingly rare in adults and no concensus regarding its diagnosis and management is available. We herein describe an elderly man with fasting hypoglycemia, inappropriate insulin hypersecretion. And pathologic examination of his pancreas revealed the characteristic finding of nesidioblastosis confirmed by immunohistochemical stain.

MeSH Terms

Adult
Aged*
Diagnosis
Humans
Hypoglycemia*
Infant, Newborn
Insulin
Islets of Langerhans
Nesidioblastosis*
Pancreas
Pancreatic Ducts
Insulin