Yonsei Med J.  1999 Jun;40(3):195-198. 10.3349/ymj.1999.40.3.195.

Serum levels of folic acid and vitamin B12 in Korean patients with vitiligo

Affiliations
  • 1Department of Dermatology, Samsung Cheil Hospital, Sungkyunkwan University School of Medicine, Suwon, Korea.
  • 2Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea. skhann@yumc.yonsei.ac.kr

Abstract

The association of vitiligo and pernicious anemia has been previously documented. The low levels of folic acid and vitamin B12 were thought to be related to vitiligo. To date, there have been very few reports about the serum levels of folic acid and vitamin B12 in patients with vitiligo. Using radioimmunoassay, we measured the serum levels of folic acid and vitamin B12 in 100 Korean patients with vitiligo. The mean serum levels of folic acid and vitamin B12 were 6.31 +/- 2.82 ng/ml and 630.25 +/- 230.94 pg/ml, respectively, in patients with vitiligo. These levels showed no significant difference compared to the normal control group, suggesting that folic acid and vitamin B12 do not appear to play a role in the pathogenesis of vitiligo.

Keyword

Folic acid; vitamin B12; vitiligo

MeSH Terms

Adolescence
Adult
Aging/blood
Child
Female
Folic Acid/blood*
Human
Male
Middle Age
Sex Characteristics
Vitamin B 12/blood*
Vitiligo/blood*
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