Yonsei Med J.
1986 Mar;27(1):67-75. 10.3349/ymj.1986.27.1.67.
Idiopathic Thrombocytopenic Purpura in Children: Clinical Prognosis and Evaluation of Treatment
- Affiliations
-
- 1Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
- KMID: 693017
- DOI: http://doi.org/10.3349/ymj.1986.27.1.67
Abstract
- A clinical study was condurted to obtain information which would make it possible to predict whether acute idiopathic thrombocytopenic purpura (ITP) will go into remission or become chronic and to evaluate the effect of treatment with steroids in acute ITP and with gammaglobulin in recurrent and chronic ITP. The most frequent clinical forms were acute ITP (69%), and thrombocytopenic purpura with antecedent viral illness was most frequent in acute ITP (83%). In acute ITP 86% of the patients had hemorrhagic symptoms of short duration, less than 2 weeks, before presentation. There was no information for making a prognosis either in the initial platelet count or in the appearance of anti-platelet antibodies. There was no definite difference in results with or without treatment with corticosteroids in acute ITP. Neither was there any definite difference in outcome for the patient of the platelet response between treatment with gammaglobulin and treatment with steroids In the chronic and recurrent forms. However; it was found that an intial platelet response to steroids may be a good prognostic sign that the acute attack will be followed by a sustained remission.
