Yonsei Med J.  1978 Jun;19(1):32-38. 10.3349/ymj.1978.19.1.32.

Biochemical Characteristics and Antibiotic Susceptibilities of Serratia marcescens Isolated from Clinical Specimens

Affiliations
  • 1Department of Clinical Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

A minimal test scheme, consisting of deoxyribonuclease (DNase) and tween 80 hydrolysis (TEH) together with a few other biochemical tests, was used to make tentative identification of Serratia marcescens from clinical specimens. The identifications were reevaluated by testing comprehensive biochemical characteristics of 52 isolates, and all were found to be correct. The biochemical reactions of the isolates were very homogenous, showing typical characteristics of the species except in the urease test and acid production from sucrose, adonitol and inositol. These facts support the feasibility of the use of the minimal identification scheme. Pigment production was noted only in 7 isolates invalidating the value of this characteristic for the identification. Fifty-seven isolates were tested for their antibiotic susceptibility. They were found most frequently susceptible to gentamicin (47.4%), chloramphenicol (35.0%) and kanamycin (28.1%). Many isolates (49.1%) were multiply resistant to ampicillin, chloramphenicol, gentamicin, kanamycin, streptomycin and tetracycline.


MeSH Terms

Antibiotics/pharmacology*
Cells, Cultured
Drug Resistance, Microbial
Human
Microbial Sensitivity Tests
Serratia marcescens/drug effects
Serratia marcescens/isolation & purification
Serratia marcescens/metabolism*
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