Yonsei Med J.  1976 Dec;17(2):151-156. 10.3349/ymj.1976.17.2.151.

The Effect of Lecucocytes on the Maturation of Mouse Oocytes in vitro

Affiliations
  • 1Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

This experiment was undertaken in order to know the effect of leucocytes on the maturation of mouse oocytes in vitro. Leucocytes obtained from heart puncture of mouse (3 X 10(4) cells/mm3) inhibited the maturation of mouse oocytes. The egg toxic activity declined with decreasing leucocyte concentration. It was found that egg toxic effect of leucocytes is not species specific. The activity of intact leucocytes or equal numbers of leucocytes that were destroyed was similar and which seems not to be influenced by the physiological stats of leucocytes.


MeSH Terms

Animal
Culture Media
Female
Leukocytes*
Metaphase
Mice
Oocytes/cytology*
Ovum/cytology*
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