Yonsei Med J.  1974 Dec;15(2):74-91. 10.3349/ymj.1974.15.2.74.

Studies on the Population of Toxigenic Fungi in Foodstuffs

Affiliations
  • 1Department of Microbiology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

These studies were carried out to detect the presence of mycotoxin producing fungi in various foodstuffs in Korea. The experiments were divided into three parts: bacteriologic, toxicologic and electron microscopic studies. From the 133 various samples, 425 colonies of fungi were isolated. In 405 of the 426 colonies it was possible to identify 17genera. Among the identified strains the predominant genera were Penicillum, Aspergillus and Alternaria. In the cytotoxicity test, 18 strains showed imld to severe toxic effects in mice, 19 strains showed toxic effects on HeLa cells. In electron microscopic studies of liver cells from aninals which had been treated with toxin-like substances, the liver cells showed the cytoplasmic changes dilatation of endoplasmic reticulum, swelling of mitochondria and increased number of lipid and glycogen particles. Alterations of nuclear envelape were also noted.


MeSH Terms

Animal
Aspergillus/isolation & purification
Cereals*
Food Microbiology*
Fungi*
Hela Cells
Human
Liver/ultrastructure
Mice
Mice, Inbred ICR
Mycotoxins/isolation & purification*
Penicillium/isolation & purification
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