Brain Tumor Res Treat.  2025 Apr;13(2):53-57. 10.14791/btrt.2024.0044.

Suprasellar Ectopic Pituitary Neuroendocrine Tumor Misdiagnosed as Pineal Parenchymal Tumor: A Case Report

• Woo SB
• Lee CY
• Kim CH
• Kwon MY
• Kim JH
• Kim SP
• Kwon SM

• KMID: 2567937
• DOI: http://doi.org/10.14791/btrt.2024.0044

Abstract

We report a rare and diagnostically challenging case of a 39-year-old male patient who presented with symptoms of dizziness and headaches, without any focal neurological symptoms. Initial imaging studies suggested a germ cell tumor, and an endoscopic biopsy led to a preliminary diagnosis of a pineal parenchymal tumor of intermediate differentiation. However, histological evaluation following surgical resection revealed the final diagnosis to be an ectopic pituitary neuroendocrine tumor (PitNET), a condition that is exceedingly rare. Ectopic PitNETs are uncommon tumors that develop outside the normal anatomical location of the pituitary gland. Their atypical presentation often leads to misdiagnosis as other intracranial neoplasms. This case highlights the diagnostic challenges posed by ectopic PitNETs and contributes to the limited literature on this rare condition. It underscores the importance of maintaining a broad differential diagnosis in patients presenting with atypical intracranial neoplasms.

Keyword

Pituitary adenoma; Pituitary neuroendocrine tumor; Pineal parenchymal tumor