Korean J Pathol.
2000 Dec;34(12):1029-1033.
Pineal Anlage Tumor: A case report
- Affiliations
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- 1Departments of Diagnostic Pathology, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul 135-710, Korea.
- 2Departments of Neurosurgery, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul 135-710, Korea.
Abstract
- The term "pineal anlage tumor" has been recently proposed and few cases have been reported. We report the first Korean case of pineal anlage tumor in a 6-year-old girl who complained of headache and vomiting for 2 months. Brain MRI revealed a well defined, lobulated, calcifying mass in the pineal region. Tumor was totally removed. Pathological examination revealed a primitive pineal parenchymal tumor with melanotic epithelial component that was similar to histologic findings of melanotic neuroectodermal tumor of infancy, so-called retinal anlage tumor and of the developing pineal gland. The tumor was composed mostly of small, undifferentiated cells, Flexner-Wintersteiner rosettes, and ganglionic differentiation. The tumor also contained the cartilage and skeletal muscle cells.
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