Korean J Geriatr Gerontol.  2017 Jun;18(1):44-47. 10.15656/kjcg.2017.18.1.44.

Cretzfeldt-Jakob Disease Mimicking Progressive Supranuclear Palsy Presenting With Supranuclear Gaze Palsy and Early Falling

Affiliations
  • 1Departments of Neurology, Ansan Hospital, Korea University College of Medicine, Ansan, Korea
  • 2Departments of Internal Medicine, Ansan Hospital, Korea University College of Medicine, Ansan, Korea

Abstract

Sporadic Creutzfeldt-Jakob disease (sCJD) is fatal prion disease typically characterized by rapid progressive dementia often associated with various movement disorders such as myoclonus and ataxia. However, atypical manifestations and varied clinical courses make timely diagnosis of sCJD difficult. Here we describe probable sCJD patients with gait disturbance and early falling as an initial clinical manifestations mimicking progressive supranuclear palsy (PSP).

Keyword

Cretzfeldt-Jakob disease; Progressive supranuclear pasly; Atypical parkinsonism; Rapidly progressive dementia
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