Prog Med Phys.  2024 Dec;35(4):106-115. 10.14316/pmp.2024.35.4.106.

Optimizing DICOM File Processing: A Comprehensive Workflow for AI and 3D Printing in Medicine

Affiliations
  • 1Department of Medicine, Yonsei University College of Medicine, Seoul, Korea
  • 2Medical Physics and Biomedical Engineering Lab (MPBEL), Yonsei University College of Medicine, Seoul, Korea
  • 3Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research, Seoul, Korea
  • 4Ewha Medical Research Institute, School of Medicine, Ewha Womans University, Seoul, Korea
  • 5Department of Biomedical Engineering, Ewha Womans University College of Medicine, Seoul, Korea
  • 6Ewha Medical Artificial Intelligence Research Institute, Ewha Womans University College of Medicine, Seoul, Korea

Abstract

Purpose
This study aims to develop a comprehensive preprocessing workflow for Digital Imaging and Communications in Medicine (DICOM) files to facilitate their effective use in AI-driven medical applications. With the increasing utilization of DICOM data for AI learning, analysis, Metaverse platform integration, and 3D printing of anatomical structures, the need for streamlined preprocessing is essential. The workflow is designed to optimize DICOM files for diverse applications, improving their usability and accessibility for advanced medical technologies.
Methods
The proposed workflow employs a systematic approach to preprocess DICOM files for AI applications, focusing on noise reduction, normalization, segmentation, and conversion to 3D-renderable formats. These steps are integrated into a unified process to address challenges such as data variability, format incompatibilities, and high computational demands. The study incorporates real-world medical imaging datasets to evaluate the workflow’s effectiveness and adaptability for AI analysis and 3D visualization. Additionally, the workflow’s compatibility with virtual environments, such as Metaverse platforms, is assessed to ensure seamless integration.
Results
The implementation of the workflow demonstrated significant improvements in the preprocessing of DICOM files. The processed files were optimized for AI analysis, yielding enhanced model performance and accuracy in learning tasks. Furthermore, the workflow enabled the successful conversion of DICOM data into 3D-printable formats and virtual environments, supporting applications like anatomical visualization and simulation. The study highlights the workflow's ability to reduce preprocessing time and errors, making advanced medical imaging technologies more accessible.
Conclusions
This study emphasizes the critical role of effective preprocessing in maximizing the potential of DICOM data for AI-driven applications and innovative medical solutions. The proposed workflow simplifies the preprocessing of DICOM files, facilitating their integration into AI models, Metaverse platforms, and 3D printing processes. By enhancing usability and accessibility, the workflow fosters broader adoption of advanced imaging technologies in the medical field.

Keyword

DICOM preprocessing; AI in medical imaging; 3D printing; Metaverse applications

Figure

  • Fig. 1 Pipeline of the CT and RT structure DICOM file preprocessing. CT, computed tomography; RT, radiotherapy; DICOM, Digital Imaging and Communications in Medicine; NIfTI, Neuroimaging Informatics Technology Initiative; STL, Stereolithography; PLY, polygon file format.

  • Fig. 2 CT and radiotherapy structure of the patient preprocessed with Neuroimaging Informatics Technology Initiative. (a, c) show the results of the preprocessed CT data, while (b, d) display the corresponding structure information for slices (a) and (c), respectively. Specifically, (b) shows the segmented left and right breasts, and (d) shows the segmented liver and spleen. CT, computed tomography.

  • Fig. 3 CT and RT structure of the patient preprocessed with STL. (a) presents the CT data converted into the STL format, while (b) shows the corresponding RT structure information converted into the STL format. The organs shown in (b) are the breasts, liver, and spleen. CT, computed tomography; STL, Stereolithography; RT, radiotherapy.


Reference

References

1. Yoon HJ, Jeong YJ, Kang H, Jeong JE, Kang DY. 2019; Medical image analysis using artificial intelligence. Prog Med Phys. 30:49–58. DOI: 10.14316/pmp.2019.30.2.49.
2. Kaur C, Garg U. 2023; Artificial intelligence techniques for cancer detection in medical image processing: a review. Materials Today. 81(Part 2):806–809. DOI: 10.1016/j.matpr.2021.04.241.
3. Koul A, Bawa RK, Kumar Y. Artificial intelligence in medical image processing for airway diseases. 2022. Connected e-Health: integrated IoT and cloud computing. Springer International Publishing;p. 217–254. DOI: 10.1007/978-3-030-97929-4_10.
4. Alnaggar OAMF, Jagadale BN, Saif MAN, Ghaleb OAM, Ahmed AAQ, Aqlan HAA, et al. 2024; Efficient artificial intelligence approaches for medical image processing in healthcare: comprehensive review, taxonomy, and analysis. Artif Intell Rev. 57:221. DOI: 10.1007/s10462-024-10814-2.
5. Ma D, Dang B, Li S, Zang H, Dong X. 2023; Implementation of computer vision technology based on artificial intelligence for medical image analysis. Int J Comput Sci Inf Technol. 1:69–76. DOI: 10.62051/ijcsit.v1n1.10.
6. Razzak MI, Naz S, Zaib A. Deep learning for medical image processing: overview, challenges and the future. 2018. Classification in BioApps: automation of decision making. Springer International Publishing;p. 323–350. DOI: 10.1007/978-3-319-65981-7_12.
7. Maier A, Syben C, Lasser T, Riess C. 2019; A gentle introduction to deep learning in medical image processing. Z Med Phys. 29:86–101. DOI: 10.1016/j.zemedi.2018.12.003. PMID: 30686613.
8. Mishra S, Tripathy HK, Acharya B. A precise analysis of deep learning for medical image processing. 2021. Bio-inspired neurocomputing. Springer International Publishing;p. 25–41. DOI: 10.1007/978-981-15-5495-7_2.
9. Singh SP, Wang L, Gupta S, Goli H, Padmanabhan P, Gulyás B. 2020; 3D deep learning on medical images: a review. Sensors (Basel). 20:5097. DOI: 10.3390/s20185097. PMID: 32906819. PMCID: PMC7570704.
10. Castiglioni I, Rundo L, Codari M, Di Leo G, Salvatore C, Interlenghi M, et al. 2021; AI applications to medical images: from machine learning to deep learning. Phys Med. 83:9–24. DOI: 10.1016/j.ejmp.2021.02.006. PMID: 33662856.
11. Dhiman G, Juneja S, Viriyasitavat W, Mohafez H, Hadizadeh M, Islam MA, et al. 2022; A novel machine-learning-based hybrid CNN model for tumor identification in medical image processing. Sustainability. 14:1447. DOI: 10.3390/su14031447.
12. Jasti VDP, Zamani AS, Arumugam K, Naved M, Pallathadka H, Sammy F, et al. 2022; Computational technique based on machine learning and image processing for medical image analysis of breast cancer diagnosis. Secur Commun Netw. 2022:1918379. DOI: 10.1155/2022/1918379.
13. López-Ojeda W, Hurley RA. 2023; Digital innovation in neuroanatomy: three-dimensional (3D) image processing and printing for medical curricula and health care. J Neuropsychiatry Clin Neurosci. 35:206–209. DOI: 10.1176/appi.neuropsych.20230072. PMID: 37448309.
14. Giannopoulos AA, Pietila T. Post-processing of DICOM images. 2017. 3D printing in medicine: a practical guide for medical professionals. Springer International Publishing;p. 23–34. DOI: 10.1007/978-3-319-61924-8_3.
15. Chotikunnan R, Chotikunnan P, Puttasakul T, Sangworasil M, Matsuura T, Thongpance N. 2017. A novel technique for 3D printer to create organ 3D model from DICOM file. Rangsit University.
16. Bansal G, Rajgopal K, Chamola V, Xiong Z, Niyato D. 2022; Healthcare in metaverse: a survey on current metaverse applications in healthcare. IEEE Access. 10:119914–119946. DOI: 10.1109/ACCESS.2022.3219845.
17. Kamio T, Suzuki M, Asaumi R, Kawai T. 2020; DICOM segmentation and STL creation for 3D printing: a process and software package comparison for osseous anatomy. 3D Print Med. 6:17. DOI: 10.1186/s41205-020-00069-2. PMID: 32737703. PMCID: PMC7393875.
18. Fogarasi M, Coburn JC, Ripley B. 2022; Algorithms used in medical image segmentation for 3D printing and how to understand and quantify their performance. 3D Print Med. 8:18. DOI: 10.1186/s41205-022-00145-9. PMID: 35748984. PMCID: PMC9229760.
19. Müller D, Kramer F. 2021; MIScnn: a framework for medical image segmentation with convolutional neural networks and deep learning. BMC Med Imaging. 21:12. DOI: 10.1186/s12880-020-00543-7. PMID: 33461500. PMCID: PMC7814713.
20. Anderson BM, Wahid KA, Brock KK. 2021; Simple python module for conversions between DICOM images and radiation therapy structures, masks, and prediction arrays. Pract Radiat Oncol. 11:226–229. DOI: 10.1016/j.prro.2021.02.003. PMID: 33607331. PMCID: PMC8102371.
21. Mamdouh R, El-Bakry HM, Riad A, El-Khamisy N. 2020; Converting 2D-medical image files "DICOM" into 3D- models, based on image processing, and analysing their results with python programming. WSEAS Trans Comput. 19:10–20. DOI: 10.37394/23205.2020.19.2.
22. Lee LK, Liew SC. 2015. Aug. 19-21. A survey of medical image processing tools. Paper presented at: 2015 4th International Conference on Software Engineering and Computer Systems (ICSECS). Kuantan, Malaysia: DOI: 10.1109/ICSECS.2015.7333105.
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