Korean J Otorhinolaryngol-Head Neck Surg.  2025 Jan;68(1):40-46. 10.3342/kjorl-hns.2024.00150.

Seven Cases of Immunoglobulin G4-Related Disease in Submandibular Glands

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Guro Hospital, Korea University College of Medicine, Seoul, Korea
  • 2Department of Pathology, Guro Hospital, Korea University College of Medicine, Seoul, Korea

Abstract

Immunoglobulin G4-related disease (IgG4-RD) is a chronic fibroinflammatory systemic disorder. Predominantly, patients with submandibular swelling are diagnosed with this disease in otorhinolaryngology. However, due to its rarity and the limited understanding of the disease, accurate diagnosis can be challenging. Through a retrospective review of seven cases of IgG4- RD patients, our study analyzed the symptoms, diagnostic approaches, treatment modalities, and prognosis of the condition, contributing to a better understanding of IgG4-RD.

Keyword

Immunoglobulin G4-related disease; Salivary gland; Submandibular gland
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