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Clinical Outcome of Parotid Gland Massage for Preventing Parotid Gland Dysfunction in Patients Treated with Radioiodine Therapy for Differentiated Thyroid Cancer: a Prospective Longitudinal Follow-Up Study

Son SH, Hong CM, Jeong SY, Lee J, Ahn BC

Background and Objectives: The aim of this study was to determine the clinical effectiveness of parotid gland (PG) massage for the prevention of PG dysfunction after administration of radioiodine (I-131)...
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Sialolithiasis of minor salivary gland: a challenging diagnostic dilemma

Matiakis A, Tzermpos F

Minor salivary gland sialolithiasis (MSGS) is a not uncommon oral mucosal disease. Its clinical appearance may mimic a mucocyst or other benign submucosal overgrowth. Stasis of saliva, which accompanies MSGS,...
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Recurred Minor Salivary Gland Cancer in Base of Tongue, Endoscopic Neck Management

Yoon SY, Lee GH, Song KJ, Cho YJ, Hong HJ

A 45-year-old female who presented with a salivary gland tumor on the oral and base of the tongue underwent surgery via intraoral approach. It led to a recurrence of the...
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Adenocarcinoma of the minor salivary gland with concurrent MAML2 and EWSR1 alterations

Choi S, Cho J, Lee SE, Baek CH, Kim YK, Kim HJ, Ko YH

Salivary gland tumors are histologically diverse, and each entity has distinctive histopathological and molecular features. We report two cases of salivary gland tumors with unique histological and molecular findings, which...
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Adjuvant Role of Botulinum Toxin A in the Management of Wounds Accompanied by Parotid Gland or Duct Injuries

Jeong Y, Lee SY, Sung KY

Background: Parotid gland or duct injuries may occur after facial trauma or surgical procedures around the parotid gland. Such injuries often cause saliva to leak into the wound, and as...
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Polymorphous Low-Grade Adenocarcinoma in the Nasopharynx: A Case Report and Review of the Literature

Polymorphous low-grade adenocarcinoma (PLGA) is a neoplasm that usually occurs in the minor salivary glands located in the mucosa of the soft and hard palates, the buccal mucosa, and the...
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Clinical Comparison of Transoral Removal with Sublingual Gland Preservation versus without Sublingual Gland Preservation versus Submandibular Gland Resection for Proximal Duct Stone of Submandibular Gland: Prospective Study

Kim G, Sung J, Jung H, Kim J, Park M, Kwon K

Background and Objectives Proximal submandibular stone is not a rare disease. The aim of this study is to evaluate the surgical outcomes of 3 different ways to treat proximal submandibular stone:...
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A retrospective cytohistological correlation of fine-needle aspiration cytology with classification by the Milan System for Reporting Salivary Gland Cytopathology

Park JH, Cha YJ, Seo JY, Lim JY, Hong SW

Background: Before publication of the new classification system named the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) in 2018, there was no standard classification for salivary gland lesions obtained...
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Ocular Surface Staining Score and Salivary Gland Scintigraphy in Patients with Primary Sjögren’s Syndrome

Park SK, Kang KD, Kim HS, Hwang HB

Purpose: To analyze the correlation between the ocular surface staining score and indices of salivary gland scintigraphy in patientswith primary Sjögren's syndrome and dry eye symptoms, and to evaluate the...
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Early management of parotid gland injury with oral nortriptyline and closed drain

Chung CM, Wee SJ, Lim H, Cho SH, Lee JW

Parotid gland plays the most critical role in saliva secretion in the oral cavity. Parotid gland injuries due to facial trauma can cause various complications such as formation of a...
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FK506 immunosuppression for submandibular salivary gland allotransplantation in rabbit

Almansoori AA, Khentii N, Ju KW, Kim B, Kim SM, Lee JH

Objectives: We compared the outcomes of two different doses of FK506 (tacrolimus) for immunosuppression in submandibular salivary gland (SMG) allotransplantation. Materials and Methods: Three SMG allotransplantation groups were established (n=6 per...
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A Case of Secretory Carcinoma of the Soft Palate

Lee JH, Ha JH, Jang JY

Secretory carcinoma of salivary gland origin is a recently described tumor that harbors a characteristic ETV6-NTRK3 translocation that is identical to secretory carcinoma of the breast. The majority of tumors...
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Changes in Protein Phosphorylation during Salivary Gland Degeneration in Haemaphysalis longicornis

Xiao Q, Hu Y, Yang X, Tang J, Wang X, Xue X, Li M, Wang M, Zhao Y, Liu J, Wang H

The ticks feed large amount of blood from their hosts and transmit pathogens to the victims. The salivary gland plays an important role in the blood feeding. When the female...
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Primary squamous cell carcinoma of the salivary gland: immunohistochemical analysis and comparison with metastatic squamous cell carcinoma

Jo U, Song JS, Choi SH, Nam SY, Kim SY, Cho KJ

Background: Primary squamous cell carcinoma (SCC) of the salivary gland is a rare disease, and distinguishing primary SCC from metastatic SCC is difficult. This study investigated the histological and immunohistochemical...
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Multiple bilateral malar mucinous cystadenomas in the minor salivary glands

Choi JH, Kim SH, Hwang JH, Kim KS, Lee SY

Mucinous cystadenoma, one of the subtypes of cystadenomas, is a rare benign salivary gland tumor. Most of the cases reported tumors presenting as asymptomatic, slow growing, single masses, primarily occurring...
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Type I Interferon Increases Inflammasomes Associated Pyroptosis in the Salivary Glands of Patients with Primary Sjögren's Syndrome

Hong SM, Lee J, Jang SG, Lee J, Cho ML, Kwok SK, Park SH

Sjögren's syndrome (SS) is a chronic and systemic autoimmune disease characterized by lymphocytic infiltration in the exocrine glands. In SS, type I IFN has a pathogenic role, and recently, inflammasome...
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Application of Developmental Principles for Functional Regeneration of Salivary Glands

Lee ES, Adhikari N, Jung JK, An CH, Kim JY, Kim JY

Currently, there has been rapid increase in the studies about salivary production because of the hyposalivation, xerostomia, caused by radiotherapy for head and neck cancer, Sjogren syndrome and aging. An...
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Primary Necrobiotic Xanthogranulomatous Sialadenitis with Submandibular Gland Localization without Skin Involvement

Kang M, Kim NR, Chung DH, Seok JY, Kim DY

Necrobiotic xanthogranulomatous reaction is a multiorgan, non-Langerhans cell histiocytosis with an unknown etiology. Occurrence in the salivary gland is extremely rare. We recently identified a case of necrobiotic xanthogranulomatous sialadenitis...
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Branchial cleft cyst in the parotid gland in a human immunodeficiency virus-negative patient

Park YY, Yoon JS, Bang SS, Ahn HC

In branchial lymphoepithelial cyst (BLEC), which is also known as branchial cleft cyst, the remnants of a branchial arch develop into a cyst, causing swelling. The first case of BLEC...
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Myxoma arising from the parotid gland

Kim SM, Kim CK, Kim SH, Lee MC, Kim JN, Choi HG, Shin DH, Jo DI

Myxomas can be divided into two groups: those derived from the facial skeleton, and those derived from external skeletal soft tissue. Soft tissue myxomas of the head and neck are...
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