Anesth Pain Med.  2024 Jul;19(3):185-193. 10.17085/apm.24069.

Regenerative therapy in geriatric patients with low back pain

• Kim J
• Bae K
• Seo JH

• KMID: 2563558
• DOI: http://doi.org/10.17085/apm.24069

Abstract

Low back pain (LBP) is a prevalent and debilitating condition, particularly among older adults, with degenerative spinal disease being a major contributor. Regenerative therapy, which aims to repair and regenerate damaged spinal structures, has shown promise in providing long-term pain relief and functional improvement. This review focuses on the application and efficacy of regenerative therapies such as mesenchymal stem cells, platelet-rich plasma, and atelocollagen in older patients with LBP. Despite the potential benefits, there is a notable scarcity of studies specifically targeting the older population, and those available often have small sample sizes and limited age-related analyses. Our findings underscore the need for more comprehensive and well-designed clinical trials to evaluate the effectiveness of these therapies in older patients. Future research should prioritize larger age-specific studies to establish regenerative therapy as a viable and effective treatment option for LBP in the aging population.

Keyword

Low back pain; Regenerative medicine; Older adults; Intervertebral disc degeneration; Stem cells; Platelet-rich plasma

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