Korean J Blood Transfus.  2024 Dec;35(3):167-177. 10.17945/kjbt.2024.35.3.1 6 7.

JR Blood Group and Anti-Jra Antibody

Affiliations
  • 1Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea

Abstract

The Jr(a+) antigen is one of the high-frequency antigens belonging to the JR blood group system. Although the clinical significance of anti-Jra is not well defined, cases of hemolytic disease of the newborn and hemolytic transfusion reactions caused by anti-Jra have been reported. This review introduces the genetic background of the JR blood group, the frequency of Jr(a+), and the clinical significance of anti-Jra based on existing literature. Additionally, it summarizes the identification of anti-Jra and the transfusion strategies that can be adopted for patients with anti-Jra alloantibodies.

Keyword

Transfusion; Erythrocytes; Blood group antigens
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