J Cardiovasc Interv.  2023 Apr;2(2):66-76. 10.54912/jci.2022.0022.

Physiologic Assessment of Coronary Artery Disease: Past, Present and Future

Affiliations
  • 1Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea

Abstract

The presence of myocardial ischemia is an important prognostic factor in patients with ischemic heart disease. Fractional flow reserve (FFR) and hyperemia-free indexes are used as invasive methods to detect and identify the ischemia-causing coronary disease. Several randomized trials and large registries proved the benefit of measuring physiologicindexes in patients with coronary artery disease. In addition, recent development of imaging and computational technologies has enabled image-based physiologic assessment and integration of imaging and physiologic information from invasive and non-invasive assessment data. In this manuscript, we review the history and current status of coronary physiologic assessment and its future perspectives.

Keyword

Myocardial fractional flow reserve; Coronary artery disease; Atherosclerotic Plaque; Nicorandil; Intravascular ultrasonography; Percutaneous coronary intervention; Prognosis
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