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Wall Shear Stress Associated with Stroke Occurrence and Mechanisms in Middle Cerebral Artery Atherosclerosis

Woo HG, Kim HG, Lee KM, Ha SH, Jo H, Heo SH, Chang Di, Liebeskind DS, Kim BJ

Background and Purpose Various mechanisms are involved in the etiology of stroke caused by atherosclerosis of the middle cerebral artery (MCA). Here, we compared differences in plaque nature and hemodynamic...
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Association between Vitamin D Status and Carotid Atherosclerosis in Korean Adults

Kim G, Kwon H

Background: Vitamin D is known to inhibit atherosclerosis through several mechanisms. This study aimed to analyze the association between vitamin D and carotid arteriosclerosis in Korean adults.  Methods: In this study,...
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Stress distribution analysis in healthy and stenosed carotid artery models reconstructed from in vivo ultrasonography

Soleimani E, Mokhtari-Dizaji M, Fatouraee N, Saberi H

Purpose: This study investigated the accuracy of models reconstructed from ultrasound image processing by comparing the radial displacement waveforms of a subject-specific artery model and evaluated stress changes in the...
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Usefulness of carotid ultrasonography and treatment of carotid disease

Kim SM, Kim YJ, Kim K, Kim BJ

Carotid stenosis is an important etiology of ischemic stroke. Most of the strokes associated with carotid stenosis are caused by artery-to-artery embolism. The risk of embolism highly depends on the...
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Understanding Vulnerable Plaques: Current Status and Future Directions

Lee KY, Chang K

The main cause of acute myocardial infarction is plaque rupture accompanied by superimposed coronary thrombosis. Thin-cap fibroatheromas (TCFAs) have been suggested as a type of lesion with a vulnerability that...
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Evaluation of Atherosclerotic Plaque in Non-invasive Coronary Imaging

Dwivedi A, Al'Aref SJ, Lin FY, Min JK

Coronary artery disease (CAD) is the leading cause of morbidity and mortality worldwide. Over the last decade coronary computed tomography angiography (CCTA) has gained wide acceptance as a reliable, cost-effective...
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Advances in Intravascular Imaging: New Insights into the Vulnerable Plaque from Imaging Studies

Yonetsu T, Jang IK

The term “vulnerable plaque” denotes the plaque characteristics that are susceptible to coronary thrombosis. Previous post-mortem studies proposed 3 major mechanisms of coronary thrombosis: plaque rupture, plaque erosion, and calcified...
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Usefulness of Plaque Magnetic Resonance Imaging in Identifying High-Risk Carotid Plaques Irrespective of the Degree of Stenosis

Lee J, Kil J, Kim DW, Kang SD

OBJECTIVE: Measurement of the degree of stenosis is not enough to decide on the treatment strategy for patients with carotid stenosis. Plaque morphology examination is needed for such a decision-making....
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Association of Neutrophil/Lymphocyte Ratio with Plaque Morphology in Patients with Asymptomatic Intermediate Carotid Artery Stenosis

Yüksel IO, Köklü E, Arslan S, Çağırcı G, Göksu EO, Koç P, Çay S, Kızılırmak F

BACKGROUND AND OBJECTIVES: Non-calcified carotid plaques are more unstable than calcified plaques, and they are associated with a higher risk of rupture, thromboembolism, and consequently, stroke. The purpose of the...
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Multimodality Intravascular Imaging Assessment of Plaque Erosion versus Plaque Rupture in Patients with Acute Coronary Syndrome

Kwon JE, Lee WS, Mintz GS, Hong YJ, Lee SY, Kim KS, Hahn JY, Sharath Kumar KS, Won H, Hyeon SH, Shin SY, Lee KJ, Kim TH, Kim CJ, Kim SW

BACKGROUND AND OBJECTIVES: We assessed plaque erosion of culprit lesions in patients with acute coronary syndrome in real world practice. SUBJECTS AND METHODS: Culprit lesion plaque rupture or plaque erosion was...
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Analysis of Plaque Composition in Coronary Chronic Total Occlusion Lesion Using Virtual Histology-Intravascular Ultrasound

Park YH, Kim YK, Seo DJ, Seo YH, Lee CS, Song IG, Yang DJ, Kim KH, Park HW, Kim WH, Bae JH

BACKGROUND AND OBJECTIVES: Success rates of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) have recently been reported to range from 80% to 90%. A better understanding of the pathologic...
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Lipoprotein-Associated Phospholipase A2 Is Related to Plaque Stability and Is a Potential Biomarker for Acute Coronary Syndrome

Chung H, Kwon HM, Kim JY, Yoon YW, Rhee J, Choi EY, Min PK, Hong BK, Rim SJ, Yoon JH, Lee SJ, Park JK, Kim MH, Jo M, Yang JH, Lee BK

PURPOSE: Plasma lipoprotein-associated phospholipase A2 (Lp-PLA2) binds to low-density lipoprotein. The levels of Lp-PLA2 reflect the plaque burden, and are upregulated in acute coronary syndrome (ACS). We investigated the diagnostic...
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Clinical Outcomes in Patients with Intermediate Coronary Stenoses: MINIATURE Investigators (Korea MultIceNter TrIal on Long-Term Clinical Outcome According to the Plaque Burden and Treatment Strategy in Lesions with MinimUm Lumen ARea lEss Than 4 mm2 Using Intravascular Ultrasound)

Hong YJ, Choi YH, Park SY, Nam CW, Cho JH, Kang WY, Lee SR, Lee SY, Kim SW, Lim SY, Yun KH, Kim JS, Kim JW, Kang WC, Kim KS, Choi JH, Chung JW, Kim SJ, Ahn Y, Jeong MH

BACKGROUND AND OBJECTIVES: We evaluated the two-year clinical outcomes in patients with angiographically intermediate lesions according to the plaque burden and treatment strategy. SUBJECTS AND METHODS: We prospectively enrolled patients with...
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Serial Changes of Coronary Atherosclerotic Plaque: Assessment with 64-Slice Multi-Detector Computed Tomography

Kim EY, Kang DK, Sun JS, Choi SY

  • KMID: 2322577
  • J Korean Soc Radiol.
  • 2013 Dec;69(6):437-447.
PURPOSE: To evaluate the progression of coronary atherosclerotic plaque during follow-up, and its association with cardiovascular risk factors. MATERIALS AND METHODS: Fifty-six atherosclerotic patients with plaque were enrolled in this retrospective...
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Comparison of Coronary Plaque Components between Non-Culprit Lesions in Patients with Acute Coronary Syndrome and Target Lesions in Patients with Stable Angina: Virtual Histology-Intravascular Ultrasound Analysis

Hong YJ, Jeong MH, Choi YH, Park SY, Rhew SH, Jeong HC, Cho JY, Jang SY, Lee KH, Park KH, Sim DS, Yoon NS, Yoon HJ, Kim KH, Park HW, Kim JH, Ahn Y, Cho JG, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: The differences in plaque characteristics between non-culprit lesions (NCL) in acute coronary syndrome (ACS) patients (ACS-NCL) and target lesions (TL) in stable angina (SA) patients (SA-TL) are...
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Prevalence and Prognostic Implication of Non-Calcified Plaque in Asymptomatic Population with Coronary Artery Calcium Score of Zero

Cho I, Suh JW, Chang HJ, Kim KI, Jeon EJ, Choi SI, Cho YS, Youn TJ, Chae IH, Kim CH, Choi DJ

BACKGROUND AND OBJECTIVES: Non-calcified plaque (NCP) identified by coronary CT angiography (CCTA) has been reported in up to 10% of individuals with coronary artery calcium score (CACS) of zero. However,...
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Effect of Adiponectin and Resistin on Coronary Plaque Composition and Coronary Artery Remodeling of Target Lesion in Patients with Stable Angina

Kim JY, Min PK, Yoon YW, Lee BK, Hong BK, Kwon HM

OBJECTIVE: The purpose of this study was to investigate the effect of adiponectin and resistin on coronary plaque composition determined by virtual histology (VH) intravascular ultrasound (IVUS) and coronary artery...
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Gadolinium-Enhanced Magnetic Resonance Imaging of Atherosclerotic Plaques in Comparison with Histopathology: An In Vivo Study in Aorta of Rabbits

Choi BW, Hur J, Lee HJ, Kim YJ, Kim TH, Choe KO

  • KMID: 1471622
  • J Korean Soc Magn Reson Med.
  • 2009 Jun;13(1):81-87.
PURPOSE: We sought to evaluate enhancement of plaque with gadolinium-based contrast agent by magnetic resonance imaging (MRI) in comparison with histopathology, namely lipid-rich and macrophage-rich components that were two representative...
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Abnormal Systemic Findings in Patients with Acute Retinal Artery Occlusion

Park SM, Kim IT

  • KMID: 2337041
  • J Korean Ophthalmol Soc.
  • 2002 Aug;43(8):1429-1434.
PURPOSE: Analyzing the systemic abnormal findings of acute retinal artery occlusion, to investigate what kinds of systemic evaluation must be performed in patients with acute retinal artery occlusion. METHODS: Thirty-three patients...
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Analysis of Intraoperative Rupture in Aneurysmal Subarachnoid Hemorrhage

Kim SS, Kim JM, Yi HJ, Bak KH, Kim CH, Kim KM, Oh SJ

  • KMID: 1904659
  • J Korean Neurosurg Soc.
  • 2002 May;31(5):445-451.
OBJECTIVE: The authors report the various factors which correlated with the intraoperative rupture during aneurysm surgery. METHODS: Retrospective study was done in patients who had been perfomed aneurysmal neck clipping by...
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