Int J Gastrointest Interv.  2024 Oct;13(4):109-113. 10.18528/ijgii240046.

How to treat liver metastases in colorectal cancer: A review

Affiliations
  • 1Oncology Unit, Casa di Cura Macchiarella S.p.A., Palermo, Italy

Abstract

Colon cancer is characterized during its history, by developing metastases in approximately 50% of patients. The organ most affected by this process is the liver and every year 900,000 new cases of colorectal cancer with liver metastases are recorded. In this disease setting, the therapeutic strategies include a combined treatment with loco-regional therapies and systemic chemotherapy treatments, with close collaboration between oncologists and surgeons. But the diversity of the clinical pictures that can present in patients with colorectal cancer liver metastases often makes it difficult to plan the sequence between surgery and chemotherapy, making it necessary to deal with these cases in a multidisciplinary team where the various professional figures discuss together individual cases to decide the best therapeutic strategy.

Keyword

Colon; Liver; Neoadjuvant therapy; Neoplasms; Surgery
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