Nat Prod Sci.  2024 Sep;30(3):208-211. 10.20307/nps.2024.30.3.208.

Argutinic acid, A New Triterpenoid from the Fruits of Actinidia arguta

Affiliations
  • 1College of Pharmacy, Chungbuk National University, Cheongju 28160, Korea
  • 2College of Natural Resources & Life Sciences, Pusan National University, Miryang 50463, Korea

Abstract

Actinidia arguta, also called as kiwiberry or hardy kiwifruit, is one of the major varieties of kiwi plants. It is small in size and has no hairs on the surface, which making it easy to be consumed. In addition, it can be cultivated in Asia, due to its cold resistance. We have been interested in the beneficial effects of the fruits of A. arguta and investigated the constituents and biological activities. A new triterpenoid, argutinic acid, along with three triterpenoids and three megastigmines were isolated from the fruits of A. arguta. The structures were determined by spectroscopic analysis including NMR, MS, UV and IR. Among the isolated compounds, two triterpenes, argutinic acid (1) and usrolic acid (4) showed α-glucosidase inhibitory activities.

Keyword

Actinidia arguta; triterpenoid; megastigmine; argutinic acid; α-glucosidase
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