J Stroke.  2024 Sep;26(3):463-467. 10.5853/jos.2024.01536.

Global Estimates of Reported Vaccine-Associated Ischemic Stroke for 1969–2023: A Comprehensive Analysis of the World Health Organization Global Pharmacovigilance Database

• Cho J
• Park J
• Jo H
• Yim Y
• Woo HG
• Oh J
• Yon DK

• KMID: 2559566
• DOI: http://doi.org/10.5853/jos.2024.01536

Figure

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  Figure 1. Global trends and geographic distribution of ischemic stroke incidence. (A) Trend of ischemic stroke reports and (B) global distribution of vaccineassociated ischemic stroke adverse events by continent.

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  Figure 2. Reported numbers of vaccine-associated ischemic stroke adverse events per year. (A) Cumulative number of reports of ischemic stroke adverse events per year in association with different vaccines. (B) Cumulative counts of ischemic stroke according to the reporting year.

Reference

References

1. Gholinataj Jelodar M, Mirzaei S, Saghafi F, Rafieian S, Rezaei S, Saatchi A, et al. Impact of vaccination status on clinical outcomes of hospitalized COVID-19 patients. BMC Infect Dis. 2024; 24:254.

2. Ihle-Hansen H, Bøås H, Tapia G, Hagberg G, Ihle-Hansen H, Berild JD, et al. Stroke after SARS-CoV-2 mRNA vaccine: a nationwide registry study. Stroke. 2023; 54:e190–e193.

3. Woo HG, Kim HJ, Park J, Lee J, Lee H, Kim MS, et al. Global burden of vaccine-associated multiple sclerosis, 1967-2022: a comprehensive analysis of the international pharmacovigilance database. J Med Virol. 2024; 96:e29591.

4. Yang H, Kim MS, Rhee SY, Lee J, Cho W, Min C, et al. National prevalence and socioeconomic factors associated with the acceptance of COVID-19 vaccines in South Korea: a large-scale representative study in 2021. Eur Rev Med Pharmacol Sci. 2023; 27:8943–8951.

5. Lee S, Jo H, Woo S, Jeong YD, Lee H, Lee K, et al. Global and regional burden of vaccine-induced thrombotic thrombocytopenia, 1969–2023: comprehensive findings with critical analysis of the international pharmacovigilance database. Eur J Haematol. 2024; Jun. 11. [Epub]. https://doi.org/10.1111/ejh.14250.

6. Kolahchi Z, Khanmirzaei M, Mowla A. Acute ischemic stroke and vaccine-induced immune thrombotic thrombocytopenia post COVID-19 vaccination; a systematic review. J Neurol Sci. 2022; 439:120327.

7. Kakovan M, Ghorbani Shirkouhi S, Zarei M, Andalib S. Stroke associated with COVID-19 vaccines. J Stroke Cerebrovasc Dis. 2022; 31:106440.

8. Hwang J, Park SH, Lee SW, Lee SB, Lee MH, Jeong GH, et al. Predictors of mortality in thrombotic thrombocytopenia after adenoviral COVID-19 vaccination: the FAPIC score. Eur Heart J. 2021; 42:4053–4063.