J Dig Cancer Res.
2024 Aug;12(2):82-89. 10.52927/jdcr.2024.12.2.82.
Colorectal Cancer and Obesity
- Affiliations
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- 1Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea
- KMID: 2559185
- DOI: http://doi.org/10.52927/jdcr.2024.12.2.82
Abstract
- The increasing prevalence of obesity globally underscores its pivotal role in the development of colorectal cancer (CRC). Epidemiological evidence consistently correlates obesity with CRC, implicating intricate pathways such as insulin resistance, chronic inflammation, and hormonal dysregulation. Understanding the impact of obesity on CRC recurrence, therapeutic efficacy, and overall survival is paramount. Lifestyle modifications, including weight reduction, offer promising avenues for mitigating CRC risk. Recognizing obesity as a modifiable risk factor highlights its importance in shaping CRC prevention and therapeutic paradigms.
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