Korean J Adult Nurs.  2024 May;36(2):160-170. 10.7475/kjan.2024.36.2.160.

Factors Influencing Sleep Quality in Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization: A Cross-Sectional Study

• Park JY
• Kim MS
• Lim HB

• KMID: 2556401
• DOI: http://doi.org/10.7475/kjan.2024.36.2.160

Abstract

Purpose
Patients with hepatocellular carcinoma may experience poor sleep quality following Transarterial Chemoembolization (TACE). This study aimed to identify factors influencing sleep quality in patients undergoing transarterial chemoembolization.
Methods
The study participants comprised 49 patients who underwent TACE and 45 nurses who cared for them. Patient data were collected through a face-to-face survey before and after TACE, as well as a review of electronic medical records. Data from nurses were collected using an online survey.
Results
The mean sleep quality score of patients with hepatocellular carcinoma undergoing TACE was 5.04±1.76. Sleep quality was negatively correlated with the number of antipyretics used (r=-.31, p=.029), anxiety (r=-.40, p=.004), postembolization syndrome (r=-.30, p=.034), and fatigue (r=-.63, p<.001), and positively correlated with the nurse’s perception of patient’s fatigue (r=.45, p=.001). In multiple regression analysis, fatigue (β=-.47, p=.001) and the number of antipyretics used (β=-.33, p=.005) explained 43.5% of the variance in patients’ sleep quality.
Conclusion
The sleep quality of patients undergoing TACE was found to be relatively low. Fatigue affects sleep quality, with more fatigued patients exhibiting poorer sleep quality. Therefore, nurses must pay attention to patient fatigue and anxiety and provide more comfortable nursing care.

Keyword

Fatigue; Hepatocellular carcinoma; Nurse; Sleep quality; Transarterial chemoembolization