Tissue Eng Regen Med.
2024 Apr;21(3):395-408. 10.1007/s13770-023-00607-z.
Strategies for Constructing Tissue-Engineered Fat for Soft Tissue Regeneration
- Affiliations
-
- 1Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou 510515, Guangdong, China
- 2Department of Plastic Surgery and Burn Center, Second Affiliated Hospital, Plastic Surgery Institute of Shantou University Medical College, Shantou 515063, Guangdong, China
- KMID: 2554990
- DOI: http://doi.org/10.1007/s13770-023-00607-z
Abstract
- BACKGROUND
Repairing soft tissue defects caused by inflammation, tumors, and trauma remains a major challenge for surgeons. Adipose tissue engineering (ATE) provides a promising way to solve this problem.
METHODS
This review summarizes the current ATE strategies for soft tissue reconstruction, and introduces potential construction methods for ATE.
RESULTS
Scaffold-based and scaffold-free strategies are the two main approaches in ATE. Although several of these methods have been effective clinically, both scaffold-based and scaffold-free strategies have limitations. The third strategy is a synergistic tissue engineering strategy and combines the advantages of scaffold-based and scaffold-free strategies.
CONCLUSION
Personalized construction, stable survival of reconstructed tissues and functional recovery of organs are future goals of building tissue-engineered fat for ATE.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Injectable Tissue-Engineered Soft Tissue for Tissue Augmentation
- Bone Regeneration from Adipose Stem Cells
- Atypical Mycobacterial Soft Tissue Infection after Autologous Fat Transplantation at Liposuction Site
- Three-Dimensional Cell-Based Bioprinting for Soft Tissue Regeneration
- Engineered Extracellular Vesicles as a Targeted Delivery Platform for Precision Therapy
