Res Community Public Health Nurs.
2024 Mar;35(1):1-9. 10.12799/rcphn.2023.00381.
Bidirectional Relationship Between Depression and Frailty in Older Adults aged 70-84 years using Random Intercepts Cross-Lagged Panel Analysis
- Affiliations
-
- 1Ph.D. Student, College of Nursing, Seoul National University, Seoul, Korea
- 2Professor, Department of Family medicine, Kyung Hee University Hospital, Seoul, Korea
- 3Professor, College of Nursing, Seoul National University ∙ Research Institute of Nursing Science, Seoul National University, Seoul, Korea
- KMID: 2553978
- DOI: http://doi.org/10.12799/rcphn.2023.00381
Abstract
- Purpose
Depression and frailty are common health problems that occur separately or simultaneously in later life. The two syndromes are correlated, but they need to be distinguished to promote successful aging. Previous studies have examined the reciprocal relationship between depression and frailty, but there are limitations in the methods or statistical analysis. This study aims to confirm the potential prospective bidirectional and causal relationship between depression and frailty.
Methods
We used data from 887 older adults aged 70 to 84 from the Korean Frailty and Aging Cohort Study (KFACS) in 2016, 2018, and 2020 (3 waves). We separated the within-individual process from the stable between-individual differences using the random intercepts cross-lagged panel model.
Results
Significant bidirectional causal effects were observed in 2 paths. Older adults with higher depression than their within-person average at T1 had a higher risk of frailty at T2 (β=.22, p=.008). Subsequently, older adults with higher-than-average frailty scores at T2 showed higher depression at T3 (β=.14, p=.010). Autoregressive effects were only significant from T2 to T3 for both constructs (Depression: β=.16, p=.044; Frailty: β=.13, p=.028). At the between-person level, the correlation was significant between the random intercepts between depression and frailty (β=.47, p<.001).
Conclusions
We find that depressed older adults have an increased risk of frailty, which contributes to the onset of depression and the maintenance of frailty. Therefore, interventions for each condition may prevent the entry and worsening of the other condition, as well as prevent comorbidity.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- The Longitudinal Relationships between Depression and Smoking in Hardcore Smokers Using Autoregressive Cross-Lagged Modeling
- The Study for Improvement of Frailty and Depression in the Health Vulnerable Elderly of Home Visiting Health Care Service
- The Reciprocal Causal Relationship between Social Activities and Health with Reference to the Cognitive Function Level among Community-dwelling Older Adults: A Cross-Lagged Panel Analysis
- Older Men Living with Spouse and Older Women Living with Spouse and Children Have Lower Frailty Prevalence: The Korean Frailty and Aging Cohort Study (KFACS)
- What are the illnesses associated with frailty in community-dwelling older adults: the Korean Frailty and Aging Cohort Study
