Precis Future Med.
2024 Mar;8(1):2-9. 10.23838/pfm.2023.00142.
Survival rate and death risk for associated pulmonary arterial hypertension: A retrospective population-based study
- Affiliations
-
- 1Department of Nursing, Yong-In Arts & Science University, Yongin, Korea
- 2Imaging Center, Heart Vascular Stroke Institute, Samsung Medical Center, Seoul, Korea
- 3The National Health Insurance Service, Wonju, Korea
- 4Central Regional Center for Disease Control and Prevention, Korea Disease Control and Prevention Agency, Seoul, Korea
- 5Department of Nursing, Gangseo University, Seoul, Korea
- 6Division of Cardiology, Department of Internal Medicine, Heart Brain Hospital, Chung-Ang University Gwangmyeong Hospital, Chung-Ang University College of Medicine, Gwangmyeong, Korea
- 7Graduate School of Clinical Nursing Science, Sungkyunkwan University, Seoul, Korea
- KMID: 2553870
- DOI: http://doi.org/10.23838/pfm.2023.00142
Abstract
- Purpose
This study aimed to assess the survival rate (SR) and death risk for associated pulmonary arterial hypertension (aPAH; 10th revision of the International Statistical Classification of Diseases [ICD-10], I27.2) in Koreans.
Methods
The data were collected from the Korean National Health Insurance Service from 2006 through 2017 (n= 15,448). We analyzed the SR using the Kaplan-Meier method and carried out Cox proportional hazards analyses.
Results
Patients’ mean age upon aPAH diagnosis was 60.1±24.0 years, and 60.7% of the patients were female. The 10-year SR of aPAH was 46.3% (95% confidence interval, 45.0 to 47.6). The factors associated with an increase in the adjusted death risk included age of 0 to 9 years, advancing age, male sex, lower income level, and comorbidities including diabetes mellitus, myocardial infarction, heart failure, hemorrhagic stroke, chronic kidney disease, malignant neoplasm, hereditary hemorrhagic telangiectasia, and systemic lupus erythematosus.
Conclusion
The 10-year SR of aPAH was over 46%. The risk of death from aPAH was significantly higher with advancing age, sex, lower income level, and comorbidities.
