Osteoporos Sarcopenia.
2023 Dec;9(4):137-141. 10.1016/j.afos.2023.10.001.
Effect of romosozumab in premenopausal women with severe osteoporosis and anorexia nervosa
- Affiliations
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- 1Department of Orthopaedic Surgery, Kohnodai Hospital, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa City, Chiba, 272-8516, Japan
- 2Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan
- KMID: 2552869
- DOI: http://doi.org/10.1016/j.afos.2023.10.001
Abstract
Objectives
This study aims to investigate the effects of romosozumab on bone mineral density (BMD) and bone metabolism.
Methods
In this retrospective case series, romosozumab was administered to 5 premenopausal female patients with osteoporosis and anorexia nervosa with fragility fractures. BMD and bone turnover marker changes were investigated at 6 months and 1 year after administering romosozumab.
Results
BMD increased and high-turnover bone metabolism decreased 6 months and 1 year after administering romosozumab.
Conclusions
Romosozumab is useful for treating osteoporosis in patients with anorexia nervosa.
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