J Korean Geriatr Psychiatry.
2023 Oct;27(2):65-70. 10.47825/jkgp.2023.27.2.
Influence of Anesthesia on Incidence of Dementias: 8-Year Follow-Up Study
- Affiliations
-
- 1Department of Psychiatry, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
- 2Department of Psychiatry, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea
- 3Department of Psychiatry, Soonchunhyang University Bucheon Hospital, Bucheon, Korea
- KMID: 2552864
- DOI: http://doi.org/10.47825/jkgp.2023.27.2
Abstract
Objective
Cognitive dysfunction is frequently reported after surgery and anesthesia in elderly patients. This study aims to investigate the incidence of dementia for eight years after anesthesia.
Methods
We extracted the data between 2007 and 2020 from the Health Insurance Review and Assessment Service Database. We analyzed risk of developing dementia after anesthesia using Cox proportional hazard models.
Results
Data were collected from 62,541 patient. Among them, subjects with and without anesthesia were 15,857 and 46,684, respectively. Subjects with anesthesia had more hypertension, diabetes mellitus and hyperlipemia than those without anesthesia. The risk of dementia incidence was found to increase 1.7 times in subjects with anesthesia (hazard ratio=1.751, 95% confidence interval=1.596-1.921). Even after the correction for gender, age, and comorbidity, the statistical significance of this risk remained (hazard ratio=1.662, 95% confidence interval=1.512-1.827).
Conclusion
Our findings suggest that anesthesia possibly contribute on cognitive impairment. Clinician might need closed
observation
on cognitive function in patients after surgery and anesthesia.
