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2023 Dec;27(4):182-195. 10.32542/implantology.2023021.
Comparative Analysis of Pre-formed 3D-Printed PCL/β-TCP Membrane Versus Collagen Membrane for Guided Bone Regeneration: A Preliminary Pilot Study
- Affiliations
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- 1Postgraduate Student, Department of Periodontology, College of Dentistry and Institute of Oral Bioscience, Jeonbuk National University, Jeonju, Korea
- 2Postgraduate Student, Department of Mechanical System Engineering, Graduate School of Knowledge-based Technology and Energy, Tech University of Korea, Siheung-si, Gyeonggi-do, Korea
- 3Director, Research & Development Center, MEGAGEN Implant Co., Ltd, Daegu, Korea
- 4Professor, Department of Mechanical Engineering, Tech University of Korea, Siheung-si, Gyeonggi-do, Korea
- 5Associate Professor, Department of Periodontology, College of Dentistry and Institute of Oral Bioscience, Jeonbuk National University and Research Institute of Clinical Medicine of Jeonbuk National University- Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea
- 6rofessor, Department of Periodontology, College of Dentistry and Institute of Oral Bioscience, Jeonbuk National University and Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea
- KMID: 2551422
- DOI: http://doi.org/10.32542/implantology.2023021
Abstract
- Purpose
This study aimed to assess and compare the effectiveness of 3D-printed pre-formed resorbable polycaprolactone/β-tricalcium phosphate (PCL/β-TCP) membrane and collagen membrane, combined with demineralized bovine bone mineral (DBBM), for guided bone regeneration (GBR) for peri-implant dehiscence defects. Materials and Methods: Twelve patients underwent GBR using either a PCL/β-TCP membrane with DBBM (PM group) or a collagen membrane with DBBM (CM group). Clinical assessments, including measurements of vertical defect height and width after implant placement (baseline) and re-entry surgery, were conducted. Cone-beam computed tomography imaging was performed to measure the augmented horizontal bone width (HW0, HW2, and HW4 at 0, 2, and 4 mm apical to the implant shoulder), vertical thickness (VT), and VT at a 45° angle (VT-45) at both time points.
Results
No adverse effects, such as soft tissue dehiscence, membrane exposure, or severe postoperative complications, were observed during the healing period. The mean reductions in the defect height and width were 89% and 80% in the PM group and 73% and 71% in the CM group, respectively. The horizontal bone width and vertical thickness between the two groups were statistically significant (p < .05) at HW0, VT, and VT-45, both at baseline and re-entry surgery. Meanwhile, the changes in bone augmentation between baseline and re-entry surgeries were not significantly different (p > .05) between the two groups.
Conclusion
Based on the findings of this study, pre-formed resorbable 3D-printed PCL/β-TCP membrane with DBBM could be an effective treatment option for peri-implant dehiscence defects, providing stability and vertical and horizontal bone augmentation.
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