Oral Biol Res.  2023 Sep;47(3):113-118. 10.21851/obr.47.03.202309.113.

Vertical and horizontal bone augmentation with three-dimensional-printed biodegradable membrane: a case report

• Bang JA
• Kim HJ
• Oh JS
• Kim JS
• Kim KW
• Moon SY

• KMID: 2546569
• DOI: http://doi.org/10.21851/obr.47.03.202309.113

Abstract

In jaw bone defects, vertical or horizontal bone augmentation is required as a regenerative procedure to restore the lost bone and to place an implant. However, this is the most challenging surgical procedure to perform. A barrier membrane that prevents soft tissue ingrowth and maintains bone volume is essential for these procedures. A bioresorbable membrane made up of biocompatible polycaprolactone (PCL) and β-tricalcium phosphate (β-TCP) has been developed recently. This PCL/β-TCP membrane is customized and fabricated in three-dimensional (3D) structures and can accurately reproduce the patient’s jaw. In this case report, vertical and horizontal augmentation was performed using a customized 3D-printed PCL/β-TCP membrane on the mandibular defect after marginal mandibulectomy in a patient with squamous cell carcinoma. The implant was placed in the augmented bone, and during the follow-up period of 25 months, it was well maintained without any complications. The customized 3D-printed PCL/β-TCP membrane with excellent biocompatibility and stability has the potential to be a predictable biomaterial.

Keyword

Biocompatible materials; Bone regeneration; Dental implant; Guided tissue regenration; 3D printing