Anxiety Mood.  2023 Oct;19(2):56-60. 10.24986/anxmod.2023.19.2.004.

A Case of a Depressed Patient With Progressive Supranuclear Palsy

• Han S
• Chang JG
• Lee SY

• KMID: 2547954
• DOI: http://doi.org/10.24986/anxmod.2023.19.2.004

Abstract

Progressive supranuclear palsy (PSP) is rare atypical Parkinsonism accompanied by various psycho-behavioural problems. In this case report, we describe the diagnostic and treatment progress of a 65-year-old PSP patient who visited the psychiatric clinic with a depressed mood and lumbar pain resulting in a suicide attempt. Over the course of 30 months of treatment, typical characteristics of PSP, such as postural instability, dyskinesia, cognitive dysfunction and supranuclear gaze palsy, became prominent, and magnetic resonance imaging and the F-18 FP-CIT positron emission tomography revealed midbrain atrophy and reduced dopamine uptake in the basal ganglia. When treating elderly patients with depression, parkinsonism symptoms such as gait disturbances, frequent falls, tremors, and rigidity should be closely examined.

Keyword

Depression; Progressive supranuclear palsy; Parkinsonism