Korean J Gastroenterol.  2023 Jul;82(1):40-42. 10.4166/kjg.2023.077.

Malignant Intraductal Papillary Neoplasm of the Bile Duct

• Jang DK

• KMID: 2544939
• DOI: http://doi.org/10.4166/kjg.2023.077

Figure

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  Fig. 1 (A) CT scan shows a 2.5 cm-sized cystic mass lesion in S8 (arrow). (B) Follow-up ultrasonography shows a 13 cm-sized large cystic mass after 7 years (arrow).

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  Fig. 2 (A) A large low-attenuated cystic mass with lobulating contour is shown on CT (arrow). (B) another cystic mass is also detected (arrow).

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  Fig. 3 PET-CT shows multiple bone metastases and peritoneal seeding.

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  Fig. 4 Pathology from percutaneous biopsy reveals atypical cells and clusters with mucin production (circle) (H&E, ×200).

Reference

1. Sakai Y, Ohtsuka M, Sugiyama H, et al. 2021; Current status of diagnosis and therapy for intraductal papillary neoplasm of the bile duct. World J Gastroenterol. 27:1569–1577. DOI: 10.3748/wjg.v27.i15.1569. PMID: 33958844. PMCID: PMC8058653.

2. Nakanuma YBO, Esposito I, Klimstra DS, Komuta M, Zen Y. 2019. Intrahepatic Cholangiocarcinoma. WHO Classification of Tumours. Medical history and perspective. 5th ed. International Agency for Research on Cancer;Lyon:

3. Nakanuma Y, Uesaka K, Miyayama S, Yamaguchi H, Ohtsuka M. 2017; Intraductal neoplasms of the bile duct. A new challenge to biliary tract tumor pathology. Histol Histopathol. 32:1001–1015.

4. Lee S, Kim MJ, Kim S, Choi D, Jang KT, Park YN. 2019; Intraductal papillary neoplasm of the bile duct: Assessment of invasive carcinoma and long-term outcomes using MRI. J Hepatol. 70:692–699. DOI: 10.1016/j.jhep.2018.12.005. PMID: 30553839.

5. Liu Y, Zhong X, Yan L, Zheng J, Liu Z, Liang C. 2015; Diagnostic performance of CT and MRI in distinguishing intraductal papillary neoplasm of the bile duct from cholangiocarcinoma with intraductal papillary growth. Eur Radiol. 25:1967–1974. DOI: 10.1007/s00330-015-3618-2. PMID: 25716939.