J Korean Ophthalmol Soc.  2023 Mar;64(3):252-255. 10.3341/jkos.2023.64.3.252.

Effect of Intravitreal Dexamethasone Implant Injection in a Patient with Recurrent Nodular Anterior Scleritis

• Kwon LH
• Kim SJ

• KMID: 2540489
• DOI: http://doi.org/10.3341/jkos.2023.64.3.252

Abstract

Purpose
To report the use of intravitreal dexamethasone implant injection in a patient with recurrent nodular anterior scleritis.
Case summary
A 16-year-old patient presented with persistent eye pain and conjunctival injection in the left eye, which were diagnosed as nodular anterior scleritis. The clinical features improved with topical and systemic steroid treatment, but the patient developed side effects related to steroid use, including elevated intraocular pressure and skin rash. The steroid dose was reduced which led to frequent recurrence. Immunosuppressive agents were added to the treatment regimen, but there was no improvement; the patient developed intermediate uveitis and vitreous hemorrhage. Scleritis and intermediate uveitis continued despite vitrectomy; therefore, intravitreal dexamethasone implant injection was performed. There was no scleritis recurrence within 1 year after injection, which allowed tapering of steroids and immunosuppressive drugs.
Conclusions
Intravitreal dexamethasone implant injection may be effective for recurrent nodular anterior scleritis in patients who exhibit complications, such as intermediate uveitis.

Keyword

Immunosuppressive agents, Intravitreal injection, Scleritis, Steroid