J Korean Acad Pediatr Dent.  2022 Nov;49(4):392-401. 10.5933/JKAPD.2022.49.4.392.

Evaluation of Acid Resistance of Demineralized Dentin after Silver Diamine Fluoride and Potassium Iodide Treatment

• Kim H
• Lee J
• Lee S
• Kim H
• Park H

• KMID: 2536593
• DOI: http://doi.org/10.5933/JKAPD.2022.49.4.392

Abstract

This study investigated the effects of silver diamine fluoride (SDF) and potassium iodide (KI) treatments on the acid resistance of dentin exposed to secondary caries. Sixteen bovine dentin specimens with artificially induced caries were assigned to the following four groups: untreated negative control, untreated positive control, SDF-treated (SDF), and SDF and KI-treated (SDFKI). Multispecies cariogenic biofilms containing Streptococcus mutans, Lactobacillus casei, and Candida albicans were cultured on the specimens for 28 days, except for the negative control group. Specimens from the negative control group were stored in phosphate-buffered saline for that period. After a cariogenic biofilm challenge, the degree of demineralization was evaluated using micro-computed tomography (micro-CT). As a result of data analysis using micro-CT, the demineralization depths of the negative control, positive control, SDF, and SDFKI groups were 149.0 ± 7 μm, 392.0 ± 11 μm, 206.0 ± 20 μm, and 230.0 ± 31 μm, respectively. The degree of demineralization was significantly reduced in the SDF and SDFKI groups compared with that in the untreated positive control group. There were no significant differences between the SDF and SDFKI groups. This study confirmed that SDF and SDFKI treatments increase the acid resistance of dentin to secondary caries. KI did not significantly affect the cariesarresting effect of the SDF.

Keyword

Silver diamine fluoride; Patassium iodide; Cariostatic agent