Kidney Res Clin Pract.
2022 Sep;41(5):591-600. 10.23876/j.krcp.22.023.
COVID-19–related clinical outcomes among Korean hemodialysis patients
- Park HC
1,2 - Lee YK1,2
- Ko E3
- Yu S4
- Cho A1,2
- Kim DH1,2
- Kim J5
- Cho JH6
- Lee J7
- Kim DK7
- Kim SN8
- Yang CW9
- on behalf of the Korean Society of Nephrology COVID-19 Task Force Team1
- Affiliations
-
- 1Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Republic of Korea
- 2Hallym Kidney Research Institute, Hallym University College of Medicine, Seoul, Republic of Korea
- 3National Emergency Medical Center, National Medical Center, Seoul, Republic of Korea
- 4Department of General Surgery, Good Samaritan Bagae Hospital, Pyeongtaek, Republic of Korea
- 5Department of Bigdata and Applied Statistics, Dongguk University, Gyeongju, Republic of Korea
- 6Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea
- 7Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
- 8Kim Seong Nam Internal Medicine Clinic, Seoul, Republic of Korea
- 9Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
- KMID: 2535404
- DOI: http://doi.org/10.23876/j.krcp.22.023
Abstract
- Background
Hemodialysis (HD) patients are more vulnerable to viral epidemics, experiencing higher mortality rates compared to individuals without chronic kidney disease (CKD). This retrospective cohort study sought to demonstrate clinical outcomes and associated factors among coronavirus disease 2019 (COVID-19) confirmed Korean HD patients. Methods: From February 2020 to November 2021, the COVID-19 Task Force Team collected clinical data for HD patients with confirmed COVID-19 via a self-report survey of nephrologists. The composite outcome included in-hospital mortality, admission to the intensive care unit (ICU), and use of mechanical ventilation. Risk factors associated with clinical outcomes were analyzed among HD patients and compared to those of individuals without CKD using the COVID-19 database from the Korea Disease Control and Prevention Agency. Results: A total of 380 HD patients from 206 facilities were diagnosed with COVID-19. Fever (49.5%) and cough (25.7%) were the two most common initial symptoms. The overall in-hospital fatality rate was 22.4% and even higher among ICU admission cases (64.7%). Non-survivors were older, more frequently developed shortness of breath, and were more likely to come from a nursing hospital. Compared to the age- and sex-matched non-CKD population, HD patients showed greater risk of in-hospital mortality (hazard ratio, 2.07; 95% confidence interval, 1.56–2.75; p < 0.001) and composite outcome (hazard ratio, 3.50; 95% confidence interval, 2.56–4.77; p < 0.001). Conclusion: HD patients have a greater risk of in-hospital mortality and morbidity from COVID-19. Special attention should be paid to COVID-19 HD patients when they are older or present with symptoms.
