- Cellular and genetic signatures of operational tolerance in kidney transplant recipients through single cell RNA sequencing analysis
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Bae H, Lee H, Ryu JH, Jang JH, Lee J, Ko GY, Yang CW, Chung BH, Oh EJ
- KMID: 2521416
- Korean J Transplant.
- 2021 Oct;35(Supple 1):S60.
- doi: 10.4285/ATW2021.PO-1109
Background: Patients with operational tolerance do not use immunosuppressants after renal transplantation, but they show stable post-transplant results as stable patients with immunosuppressants. We analyzed differently expressed mRNAs and proteins... -
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- Intra-patient variability in tacrolimus trough levels over 2 years affects long-term allograft outcomes of kidney transplantation
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Park Y, Lee H, Eum SH, Kim HD, Ko EJ, Yang CW, Chung BH
- KMID: 2521388
- Korean J Transplant.
- 2021 Oct;35(Supple 1):S88.
- doi: 10.4285/ATW2021.OP-1118
Background: The current study aimed to determine the impact of tacrolimus (TAC) trough level (C0) intra-patient variability (IPV) over 2 years after kidney transplantation (KT) on allograft outcomes. Methods: In total,... -
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- Changing patterns of T lymphocyte subsets after kidney transplantation according to induction immunosuppressant: single center prospective observational study
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Kim HD, Bae H, Eum SH, Lee H, Ko EJ, Yang CW, Oh EJ, Chung BH
- KMID: 2521382
- Korean J Transplant.
- 2021 Oct;35(Supple 1):S94.
- doi: 10.4285/ATW2021.OP-1147
Background: The aim of this study is to investigate the changing patterns of T cell subsets during early post-transplant period according to the type of induction therapy (anti-thymocyte globulin [ATG]... -
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- Comparison of the impact between peak mean fluorescent intensity versus sum of mean fluorescent intensity value of donor specific anti-human leukocyte antigen antibody on the posttransplant clinical outcomes
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Kim HD, Park Y, Eum SH, Lee H, Ko EJ, Yang CW, Chung BH
- KMID: 2521381
- Korean J Transplant.
- 2021 Oct;35(Supple 1):S95.
- doi: 10.4285/ATW2021.OP-1148
Background: In this study, we investigated to verify which of the peak value of donor-specific human leukocyte antigen antibodies (DSA) mean fluorescent intensity (MFI) and sum of MFI had higher... -
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- Water-soluble coenzyme Q10 provides better protection than lipid-soluble coenzyme Q10 in a rat model of chronic tacrolimus nephropathy
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Cui S, Luo K, Quan Y, Lim SW, Shin YJ, Lee KE, Kim HL, Ko EJ, Kim JH, Chung SJ, Bae SK, Chung BH, Yang CW
- KMID: 2517812
- Korean J Intern Med.
- 2021 Jul;36(4):949-961.
- doi: 10.3904/kjim.2020.211
Background/Aims: Coenzyme Q10 (CoQ10), is a promising antioxidant; however, low bioavailability owing to lipid-solubility is a limiting factor. We developed water-soluble CoQ10 (CoQ10-W) and compared its effects with conventional lipid-soluble... -
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- Impact of high body mass index on allograft outcomes in kidney transplant recipients with presensitization to human leukocyte antigen
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Park Y, Lee H, Ko EJ, Lee S, Ban TH, Min JW, Yoon HE, Oh EJ, Yang CW, Chung BH
- KMID: 2520046
- Kidney Res Clin Pract.
- 2021 May;40(2):304-316.
- doi: 10.23876/j.krcp.20.216
Background: This study aimed to investigate whether high body mass index (BMI) and presensitization to human leukocyte antigen (HLA) in kidney transplant recipients (KTRs) affected allograft outcomes. Methods: From January 2010... -
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- Impact of acute kidney injury in deceased donors with high Kidney Donor Profile Index on posttransplant clinical outcomes: a multicenter cohort study
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Park WY, Chang YK, Kim YS, Jin K, Yang CW, Han S, Chung BH
- KMID: 2514895
- Kidney Res Clin Pract.
- 2021 Mar;40(1):162-174.
- doi: 10.23876/j.krcp.20.083
Background: This study evaluated the impact of acute kidney injury (AKI) on posttransplant clinical outcomes for deceased donor (DD) kidney transplantation (KT) using the Kidney Donor Profile Index (KDPI) system.... -
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- L-carnitine treatment attenuates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
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Zhao HY, Li HY, Jin J, Jin JZ, Zhang LY, Xuan MY, Jin XM, Jiang YJ, Zheng HL, Jin YS, Jin YJ, Choi BS, Yang CW, Piao SG, Li C
- KMID: 2513826
- Korean J Intern Med.
- 2021 Mar;36(Suppl 1):S180-S195.
- doi: 10.3904/kjim.2019.413
Background/Aims: Accumulating evidence indicates that L-carnitine (LC) protects against multiorgan damage through its antioxidant properties and preservation of the mitochondria. Little information is available about the effects of LC on... -
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- Mortality prediction of serum neutrophil gelatinase-associated lipocalin in patients requiring continuous renal replacement therapy
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Park Y, Ban TH, Kim HD, Ko EJ, Lee J, Kim SC, Park CW, Yang CW, Kim YS, Chung BH
- KMID: 2513750
- Korean J Intern Med.
- 2021 Mar;36(2):392-400.
- doi: 10.3904/kjim.2019.446
Background/Aims: We investigated whether serum neutrophil gelatinase-associated lipocalin (NGAL) can predict mortality in patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT). Methods: This study enrolled 169 patients... -
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- Usefulness of BK virus-specific interferon-γ enzyme-linked immunospot assay for predicting the outcome of BK virus infection in kidney transplant recipients
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Bae H, Na DH, Chang JY, Park KH, Min JW, Ko EJ, Lee H, Yang CW, Chung BH, Oh EJ
- KMID: 2509769
- Korean J Intern Med.
- 2021 Jan;36(1):164-174.
- doi: 10.3904/kjim.2019.339
Background/Aims To investigate if BK virus (BKV)-specific T cell immunity measured by an interferon-γ enzyme-linked immunospot (ELISPOT) assay can predict the outcome of BK virus infection in kidney transplant recipients (KTRs). Methods We... -
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- Acute allograft dysfunction mimicking thrombotic microangiopathy in kidney transplant recipient with renal infarction: case report and review of literatures
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Lee S, Ho LY, Chung BH, Park SC, Yang CW
- KMID: 2510266
- Korean J Transplant.
- 2020 Dec;34(4):272-278.
- doi: 10.4285/kjt.20.0034
Acute allograft dysfunction is rarely observed in kidney transplantation (KT). We report an unusual case of acute allograft dysfunction mimicking thrombotic microangiopa- thy (TMA) in recipient with renal infarction. A 65-year-old man... -
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- Differential impact of allograft rejection on kidney transplant patients with BK virus infection
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Min JW, Park JB, Park JH, Park JW, Yang J, Ahn C, Yang CW, Chung BH
- KMID: 2509241
- Korean J Transplant.
- 2020 Dec;34(Supple 1):S93.
- doi: 10.4285/ATW2020.PO-1238
Background: BK virus-associated nephropathy (BKVAN) is a known risk factor for allograft dysfunction and graft failure in kidney transplant recipients. The mainstay of treatment for BKVAN is reduction of immunosuppression... -
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- Usefulness of pre- and post-transplant BK virus-specific ELISPOT assay for predicting the outcome of BK virus infection in kidney transplant recipients
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Ko EJ, Bae H, Park KH, Yang CW, Chung BH, Oh EJ
- KMID: 2509197
- Korean J Transplant.
- 2020 Dec;34(Supple 1):S54.
- doi: 10.4285/ATW2020.OP-1144
Background: To investigate if BK virus (BKV)-specific T cell immunity measured by an interferon-γ enzyme-linked immunospot (ELISPOT) assay at pre- and post-transplant can predict the outcome of BKV infection in kidney... -
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- The clinical utility of preformed C1q-binding donor-specific anti-HLA antibodies in kidney transplantation
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Lee S, Yang CW, Chung BH
- KMID: 2509182
- Korean J Transplant.
- 2020 Dec;34(Supple 1):S48.
- doi: 10.4285/ATW2020.OP-1158
Background: The role of C1q-binding donor-specific antibody (DSA) in antibody-mediated rejection (AMR) is considered important. De novo C1q-binding DSA is well known as an associated factor for increased risk of... -
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- The clinical impact of preformed human leukocyte antigen-DQ donor-specific antibodies on graft outcomes in kidney transplantation
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Lee S, Chung BH, Yang CW
- KMID: 2509181
- Korean J Transplant.
- 2020 Dec;34(Supple 1):S47.
- doi: 10.4285/ATW2020.OP-1156
Background: De-novo human leukocyte antigen (HLA)-DQ donor-specific antibody (DSA) is well known as a risk factor for graft dysfunction and graft loss in kidney transplantation (KT). Recently, the influence of... -
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- Changes of T lymphocyte subsets after kidney transplantation according to induction immunosuppressants
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Kim HD, Bae H, Yang CW, Oh EJ, Chung BH
- KMID: 2509179
- Korean J Transplant.
- 2020 Dec;34(Supple 1):S46.
- doi: 10.4285/ATW2020.OP-1096
Background: The aim of this study is to investigate the change of T cell subsets during early post-transplant period according to the type of induction therapy (anti-thymocyte globulin [ATG] vs.... -
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- Human leukocyte antigen-DR/DQ eplet mismatch analysis for primary alloimmune risk stratification of non-sensitized kidney transplant recipients
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Lee H, Min JW, Kang H, Yang CW, Chung BH, Oh EJ
- KMID: 2509134
- Korean J Transplant.
- 2020 Dec;34(Supple 1):S14.
- doi: 10.4285/ATW2020.OP-1071
Background: Human leukocyte antigen (HLA) analysis has been suggested as a predictive tool for alloimmune risk stratification in kidney transplantation (KT). We investigated whether the whole or single molecule HLA... -
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- Combined impact of pre-sensitization and delayed graft function on the development of allograft rejection in deceased donor kidney transplantation: nationwide cohort study
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Lee H, Park Y, Ban TH, Song SH, Song SH, Yang J, Ahn C, Yang CW, Chung BH
- KMID: 2509124
- Korean J Transplant.
- 2020 Dec;34(Supple 1):S4.
- doi: 10.4285/ATW2020.OP-1094
Background: Both pre-sensitization to human leukocyte antigen and delayed graft function (DGF) is well documented to be associated with poor allograft outcome. The aim of this study is to investigate... -
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- Impact of kidney and recipient weight incompatibility on the allograft outcomes in kidney transplant recipients with pre-transplant diabetes mellitus: a single center retrospective cohort study
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Park Y, Lee H, Ko J, Yang CW, Chung BH
- KMID: 2509123
- Korean J Transplant.
- 2020 Dec;34(Supple 1):S3.
- doi: 10.4285/ATW2020.OP-1046
Background: The aim of this study was to analyze the impact on the adverse allograft outcome of transplanting relatively small kidneys in patients with pre-transplant diabetes mellitus (DM). Methods: From January... -
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- Clinical outcomes of infection-related hospitalization in incident peritoneal dialysis patients
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Jeon Y, Kim HD, Hong YA, Kim HW, Yang CW, Chang YK, Kim YK
- KMID: 2509807
- Kidney Res Clin Pract.
- 2020 Dec;39(4):460-468.
- doi: 10.23876/j.krcp.20.069
Background: Infection is the second leading cause of death in patients undergoing long-term dialysis. Peritoneal dialysis (PD) is associated with an increased risk of infection-related hospitalization (IRH) when compared with... -
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