J Korean Ster Func Neurosurg.  2021 Sep;17(2):78-82. 10.52662/jksfn.2021.00101.

A review of neurosurgical manifestations related to COVID-19

• Kim J
• Park Ys
• Namgung WC
• Oh S

• KMID: 2534576
• DOI: http://doi.org/10.52662/jksfn.2021.00101

Abstract

Humans have experienced several pandemics of infectious diseases in history; for instance, many deaths occurred due to smallpox, plague, and Spanish influenza. Unlike in the past, it is now possible to establish the causes of diseases medically, and many analytical and preventive methods have been developed. Humankind is striving to improve our collective understanding of infectious diseases and to resolve epidemics. During the coronavirus disease 2019 (COVID-19) pandemic, millions of people have suffered from this viral disease. Although COVID-19 is primarily a respiratory infection, neurological symptoms have appeared in many patients. The symptoms and sequelae of nervous system invasion by severe acute respiratory syndrome (SARS)-CoV-2, the causative agent of COVID-19, must be thoroughly investigated and dealt with. Although no studies have analyzed the effects of the Spanish influenza on the nervous system, research has been conducted on nervous system involvement in previous outbreaks of coronaviruses, including SARS and Middle East respiratory syndrome (MERS). The route of virus invasion, the mechanism of damage to the nervous system, the occurrence of symptoms, and sequelae have been studied. SARS-CoV-2 invades the nervous system in a similar way and causes symptoms. Several research papers on this topic are reviewed herein.

Keyword

COVID-19; Central nervous system; Manifestation