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Successful Treatment of Isolated Central Nervous System Relapse with Intrathecal Chemotherapy in an Adolescent with Acute Promyelocytic Leukemia

Song H, Yi ES

Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML) characterized by translocation of chromosomes 15 and 17 (t(15;17)), which rarely occurs in the pediatric population. Isolated central...
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Rotavirus infection-associated central nervous system complications: clinicoradiological features and potential mechanisms

Lee KY

Despite the introduction of vaccines in 2006, rotavirus remains one of the most common causes of pediatric gastroenteritis worldwide. While many studies have conclusively shown that rotavirus infection causes gastroenteritis...
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Fetus Prenatally Diagnosed with Lobar Holoprosencephaly Postnatally Diagnosed with Simple Hydrocephalus with Good Prognosis: A Case Report

Moon H, Kim EH

Hydrocephalus is ventriculomegaly caused by an increased pressure of the cerebrospinal fluid within the ventricles of the brain. As uncomplicated hydrocephalus rarely has fatal outcomes, it stands in contrast to...
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Use of a Rigid-Tipped Microguidewire for the Endovascular Treatment of Cavernous Sinus Dural Arteriovenous Fistulas with an Occluded Inferior Petrosal Sinus

Deniwar MA, Kwon B, Song Y, Park JC, Lee DH

Objective : Transvenous embolization (TVE) via an occluded inferior petrosal sinus (IPS) in a cavernous sinus dural arteriovenous fistula (CSDAVF) is challenging, often requiring navigation of a microcatheter through resistive...
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Delivering Speech by Non-Invasive Electric Stimulation of the Central Nervous System

Suh MW

Recent advances in neuroscience and precise electric stimulation have enabled us to deliver complex signals to the central nervous system. But most of the successful electric stimulation devices such as...
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Relationships of autonomic dysfunction with disease severity and neuropathic pain features in fibromyalgia: is it really a sympathetically maintained neuropathic pain?

On AY, Tanigor G, Baydar DA

Background: The pathophysiology of fibromyalgia (FM) involves many mechanisms including central nervous system sensitization theory, autonomic nervous system (ANS) dysfunction, and recently small fiber neuropathy. While the small fiber neuropathy...
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Reversible Symptom Aggravation by Intake of Taurine-Rich Foods in Patients with Venous Congestive Myelopathy: Controlled Case Series Study

Suh DC, Jeong S, Choi YH, Cho SM, Yun SY, Son AY, Lim YM, Kwon B, Song Y

Purpose: Reversible aggravation of myelopathy symptoms was observed after the intake of taurine-rich foods in patients with venous congestive myelopathy (VCM) caused by a spinal arteriovenous shunt (SAVS), and the...
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Assessment and Comparison of Three Dimensional Exoscopes for Near-Infrared Fluorescence-Guided Surgery Using Second-Window Indocyanine-Green

Cho SS, Teng CW, De Ravin E, Singh YB, Lee JY

Objective : Compared to microscopes, exoscopes have advantages in field-depth, ergonomics, and educational value. Exoscopes are especially well-poised for adaptation into fluorescence-guided surgery (FGS) due to their excitation source, light...
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Hypo-trimethylation of Histone H3 Lysine 4 and Hyper-tri/dimethylation of Histone H3 Lysine 27 as Epigenetic Markers of Poor Prognosis in Patients with Primary Central Nervous System Lymphoma

Kim HG, Kim MS, Lee YS, Lee EH, Kim DC, Lee SH, Kim YZ

Purpose This study aimed to investigate the methylation status of major histone modification sites in primary central nervous system lymphoma (PCNSL) samples and examine their prognostic roles in patients with PCNSL....
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Childhood Primary Angiitis of the Central Nervous System Presenting as Isolated Middle Cerebral Artery Dissection

Chung M, Shin Yw, Kwon HM

Isolated middle cerebral artery dissection and primary angiitis of the central nervous system are two rare but serious causes of ischemic stroke in children. We report a case of a...
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Acute Stroke Caused by Large Vessel Vasculitis in a Patient with Systemic Lupus Erythematosus

Lee MA, Hwang BW, Lee DK, Lee CJ, Kim JH, Ahn SH

Systemic lupus erythematosus is an uncommon cause of ischemic stroke. The subcortical and periventricular white matter are most commonly involved in the central nervous system. Although vasculitis is the most...
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Cranial and Spinal Window Preparation for in vivo Optical Neuroimaging in Rodents and Related Experimental Techniques

Yeon C, Im JM, Kim M, Kim YR, Chung E

  • KMID: 2531117
  • Exp Neurobiol.
  • 2022 Jun;31(3):131-146.
  • doi: 10.5607/en22015
Optical neuroimaging provides an effective neuroscience tool for multi-scale investigation of the neural structures and functions, ranging from molecular, cellular activities to the inter-regional connectivity assessment. Amongst experimental preparations, the...
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Pathological brain lesions in girls with central precocious puberty at initial diagnosis in Southern Vietnam

Huynh QTV, Ho BT, Le NQK, Trinh TH, Lam LHT, Nguyen NTK, Huang SY

Purpose: Cranial magnetic resonance imaging (MRI) is recommended to identify intracranial lesions in girls with central precocious puberty (CPP). Yet, the use of routine MRI scans in girls with CPP...
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A Practical Grading Scale for Predicting Outcomes of Radiosurgery for Dural Arteriovenous Fistulas: JLGK 1802 Study

Hasegawa H, Shin M, Kawagishi J, Jokura H, Hasegawa T, Kato T, Kawashima M, Shinya Y, Kenai H, Kawabe T, Sato M, Serizawa T, Nagano O, Aoyagi K, Kondoh T, Yamamoto M, Onoue S, Nakazaki K, Iwai Y, Yamanaka K, Hasegawa S, Kashiwabara K, Saito N, on Behalf of the JLGK 1802 Study Group

Background and Purpose To assess the long-term outcomes of intracranial dural arteriovenous fistula (DAVF) treated with stereotactic radiosurgery (SRS) alone or embolization and SRS (Emb-SRS) and to develop a grading...
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Long-Term Management of Seizures after Surgical Treatment of Supratentorial Cavernous Malformations : A Retrospective Single Centre Study

Dziedzic TA, Koczyk K, Nowak A, Maj E, Marchel A

Objective : Seizure recurrence after the first-ever seizure in patients with a supratentorial cerebral cavernous malformation (CCM) is almost certain, so the diagnosis and treatment of epilepsy is justified. The...
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Intraventricular Antimicrobial Therapy for Intractable Ventriculitis: Two Case Reports

Lee JW, Yoon Y, Kim SD, Kim YK

It is challenging to treat ventriculitis with parenteral treatment alone in some cases because of the difficulty involved in maintaining an appropriate level of antibiotics in cerebrospinal fluid (CSF). We...
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Effectiveness of graded motor imagery in subjects with frozen shoulder: a pilot randomized controlled trial

Gurudut P, Godse AN

Background: Subjects with frozen shoulder (FS) might not be comfortable with vigorous physical therapy. Clinical trials assessing the effect of graded motor imagery (GMI) in FS are lacking. The aim...
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Homeostatic Regulation of Glucose Metabolism by the Central Nervous System

Choi JH, Kim MS

Evidence for involvement of the central nervous system (CNS) in the regulation of glucose metabolism dates back to the 19th century, although the majority of the research on glucose metabolism...
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Nosocomial meningitis in intensive care: a 10-year retrospective study and literature review

Valdoleiros SR, Torrão C, Freitas LS, Mano D, Gonçalves C, Teixeira C

Background: Nosocomial meningitis is a medical emergency that requires early diagnosis, prompt initiation of therapy, and frequent admission to the intensive care unit (ICU). Methods: A retrospective study was conducted...
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Diffuse large B-cell lymphoma presenting as transverse myelitis

Zukhriddin U, Kang JJ, Jeong MJ, Oh SY

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin’s lymphoma. Although progressive lymphadenopathy is a typical feature, extranodal involvement may also occur, including the gastrointestinal tract, skin,...
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