J Korean Orthop Assoc.  2022 Oct;57(5):363-370. 10.4055/jkoa.2022.57.5.363.

Regenerative Medicine for Musculoskeletal Diseases

• Choi YS
• Lee CE
• Lee YK

• KMID: 2534389
• DOI: http://doi.org/10.4055/jkoa.2022.57.5.363

Abstract

Regenerative medicine (RM) aims to replace or regenerate human cells, tissues, or organs to restore or establish the normal function. RM comprises cells, biomaterials for scaffolds, and growth factors. The cells play an important role in regenerative medicine. Biomaterials can form tissue and transmit biological activity signals and promote cell adhesion. The biological growth factor is a signal transmitter necessary to regenerate tissues and organs. Bioprinting as a powerful tool for building tissue and organ structures in the field of tissue engineering has attracted enormous attention as a fabrication methodology for producing 3-dimensional structures. Bioprinting technology will be needed to treat musculoskeletal diseases. This paper will provide information that can be used as a regenerative medicine treatment for musculoskeletal diseases. It will enable the regeneration of the musculoskeletal system consisting of bones, joints, muscles, and nerves.

Keyword

regenerative medicine; biocompatible materials; tissue engineering; musculoskeletal system; bioprinting