Med Lasers.  2022 Mar;11(1):8-14. 10.25289/ML.2022.11.1.8.

Appraisal of Recent Developments in Combined Photodynamic Treatment (PDT)/Photobiomodulation (PBM) for Dermal Wound Healing

• Padalhin A

• KMID: 2533540
• DOI: http://doi.org/10.25289/ML.2022.11.1.8

Abstract

Phototherapy has come a long way from simply relying on sunlight as a light source for the treatment of various dermatological conditions. Several new developments have already found application in clinical settings, and further investigations are currently advancing its utility in combination with other therapeutic approaches. This review presents data from select publications with novel (stand-alone or combined) photodynamic therapy (PDT) and photobiomodulation (PBM) for dermal wound management and skin tissue regeneration. This article specifically includes several therapeutic approaches combined with either photodynamic therapy or photobiomodulation which uses red to near-infrared wavelengths. The noteworthy approaches detailed in the article include the use of PDT for anti-microbial applications; PBM for the management of adverse effects of toxins; dual-wavelength light therapy; the use of PBM with hydrogels; and the combined application of either drug or naturally derived therapeutic agents with PBM.

Keyword

Photobiomodulation; Photodynamic therapy; Combined therapy; Hydrogel; Skin regeneration