Med Lasers.  2020 Dec;9(2):119-125. 10.25289/ML.2020.9.2.119.

Effect of Photobiomodulation on the Mesenchymal Stem Cells

• Yoo SH

• KMID: 2533477
• DOI: http://doi.org/10.25289/ML.2020.9.2.119

Abstract

Photobiomodulation forms the basis of photomedicine and is defined as the effect of coherent or non-coherent light sources, such as low-level lasers and light-emitting diodes, on cells and tissues. This treatment technique affects cell functions, proliferation, and migration, and plays an important role in tissue regeneration. Mesenchymal stem cells (MSCs) are known to be beneficial for tissue regeneration, and the combination of stem cell therapy and laser therapy appears to positively affect treatment outcomes. In general, a low-power laser has a positive effect on MSCs, thereby facilitating improvements in different disease models. This study elucidates the mechanisms and effects of low-power laser irradiation on the proliferation, migration, and differentiation of various MSCs that have been examined in different studies.

Keyword

Photobiomodulation; Mesenchymal stem cell; Laser; Low-level lasers