Korean J Gastroenterol.  2022 Jul;80(1):43-46. 10.4166/kjg.2022.083.

Kaposi Sarcoma Involving Skin and Stomach

Affiliations
  • 1Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea


Figure

  • Fig. 1 Disseminated skin lesion. Disseminated brownish multiple papule-like lesions on both neck and chest. Biopsy showed atypical vascular proliferative lesion, human herpes virus-8 positive lesion, consistent with cutaneous Kaposi sarcoma.

  • Fig. 2 Abdomen-pelvis computed tomography (CT). Abdomen-pelvis CT revealed small prominent lymph nodes in the mesentery of unclear etiology, mild edematous wall thickening of the stomach and the small bowel.

  • Fig. 3 Positron emission tomography-computed tomography. Hypermetabolic lesions suggesting Kaposi sarcoma in both lower neck, central neck, Lt. deltoid muscle.

  • Fig. 4 Esophagogastroduodenoscopy. (A-D) Esophagogastroduodenoscopy showed numerous hyperemic maculopapular and polypoid lesions disseminated in whole stomach.

  • Fig. 5 Endoscopic biopsy specimen of stomach lesions. (A) Hematoxylin and eosin stain (×400) showed atypical (spindle-shaped) endothelial cell proliferation. (B) Atypical endothelial cells with HHV-8 (immunohistochemistry, ×400) expression (red circles). (C) Atypical cells with CD31 (immunohistochemistry, ×400) expression.


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