Ann Dermatol.  2016 Dec;28(6):749-752. 10.5021/ad.2016.28.6.749.

Hidden Pictures of Kaposi's Sarcoma in Psoriatic Lesions: A Diagnostic Challenge

• Yoo J
• Jo M
• Kim MS
• Choi KH
• Park HJ
• Jue MS

• KMID: 2368126
• DOI: http://doi.org/10.5021/ad.2016.28.6.749

Abstract

Kaposi's sarcoma is a multifocal proliferative vascular tumor involving the skin and other organ and psoriasis is a chronic cutaneous disease with papules and plaques with white scale. Development of Kaposi's sarcoma in psoriasis patients has been reported rarely. A 71-year-old man presented with multiple brownish to violaceous plaques on both feet and arms which were found 4 months ago. The biopsy confirmed Kaposi's sarcoma. The patient was diagnosed with psoriasis vulgaris 10 years ago and Kaposi's sarcoma lesions developed between psoriatic plaques. We herein report a rare case of simultaneous occurrence of Kaposi's sarcoma and psoriasis vulgaris which need quite different treatment.

Keyword

Kaposi's sarcoma; Psoriasis

MeSH Terms

Aged
Arm
Biopsy
Foot
Humans
Psoriasis
Sarcoma, Kaposi*
Skin

Figure

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  Fig. 1 (A, B) Multiple red-brown papules and violaceous plaques on both legs and feet.

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  Fig. 2 (A) A few angiomatous papules between psoriatic plaques on the elbow. (B) Violaceous lesions suspicious of Kaposi's sarcoma were hidden between extensive psoriatic lesions in clinical photos taken nine months ago. (C) Closer view (arrows: violaceous lesions suspicious of Kaposi's sarcoma between psoriatic lesions).

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  Fig. 3 (A) Extensive vascular proliferation with multiple dilated vascular spaces of back-to-back configuration and spindle shaped cells in the dermis (H&E, ×100). (B) Positive for human papillomavirus-8 (HHV-8 immunohistochemistry stain, ×100).

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