J Korean Neurol Assoc.  2022 Aug;40(3):228-234. 10.17340/jkna.2022.3.2.

Suicidality and Its Risk Factor in Migraine Patients

• Seo JG
• Kim BK
• Chu MK
• Cho SJ
• Chung PW
• Moon HS
• Kim BS
• Ahn JY
• Sohn JH
• Chung JM
• Choi YJ
• Moon HJ
• Park SP

• KMID: 2532118
• DOI: http://doi.org/10.17340/jkna.2022.3.2

Abstract

Background
Migraine patients have a higher frequency of suicidality than people without migraine. The aim of this study was to identify suicidality and its risk factors in migraine patients.
Methods
We enrolled 358 migraine patients from 11 hospitals. We collected data regarding their clinical characteristics and the patients completes the questionnaires. We also interviewed patients with the Mini International Neuropsychiatric Interview (MINI)plus version 5.0.0 to identify their suicidality. The International Classification of Headache Disorders, third edition, beta version was used in headache diagnosis.
Results
The frequency of suicidality in migraine patients was 118 (33.0%). Migraine patients with suicidality were more likely to have a major depressive disorder or generalized anxiety disorder than those without suicidality. Among variables, risk factors for suicidality in migraine patients were female (odds ratio [OR], 4.110; 95% confidence interval [CI], 1.55310.878; p=0.004), attack duration (OR, 2.559; 95% CI, 1.2105.413; p=0.011), Patient Health Questionnaire9 (OR, 1.111; 95% CI, 1.0381.189; p=0.002), and Generalized Anxiety Disorder7 (OR, 1.194; 95% CI, 1.1011.294; p<0.001).
Conclusions
Suicidality in migraine patients is common. Therefore, clinicians who take care of migraine patients should be concerned about suicidality and its risk factors such as female gender, attack duration, depression or anxiety.

Keyword

Migraine disorders; Female; Depression; Anxiety