J Rhinol.  2022 Jul;29(2):96-100. 10.18787/jr.2022.00402.

Optical Analysis of Nasal Endoscopic Images From a Patient With Severe Acute Respiratory Syndrome Coronavirus 2

• Bae S
• Jun YJ

• KMID: 2532011
• DOI: http://doi.org/10.18787/jr.2022.00402

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide; a simple diagnostic test is becoming increasingly important. Polymerase chain reaction tests of nasal swab samples are expensive and time-consuming. Detailed observation of the nasal cavity is required. No nasal endoscopic study regarding patients with SARS-CoV-2 has been published. Here, we compared endoscopic images of normal subjects and patients with allergic rhinitis (AR) to images from a patient with confirmed SARS-CoV-2 infection. Nasal cavity endoscopic images (of the inferior turbinate) were compared using the hue, saturation, and luminance (HSL) color system of Matrox Design Assistant, version 5.0. The multiple allergen simultaneous test was used to distinguish normal subjects from patients with AR. HSL patterns were compared among images. We enrolled 14 normal subjects and patients with AR and 1 patient with confirmed SARS-CoV-2 infection. The inferior turbinates of normal subjects and patients with AR were smooth and uniform, while those of the patient with SARS-CoV-2 were scratched and stretched. Although additional data are needed, optical analysis of nasal endoscopy images may be useful to screen for SARS-CoV-2 infection. This imaging method is rapid, non-invasive, and inexpensive.

Keyword

SARS-CoV-2; Endoscopes; Nasal mucosa; Optical imaging; Turbinates

Figure

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  Fig. 1 Optical analysis of nasal endoscopic images from a patient with SARS-CoV-2. Upper six panels: right side, lower six panels: left side. The overall pattern was revealed by hue analysis. The scratch pattern was revealed by luminance analysis. The nasal mucosa of the patient with SARS-CoV-2 exhibited widespread spikes or scratches. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; HSL, hue, saturation, and luminance.

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  Fig. 2 Optical analysis of nasal endoscopic images from normal subject and patient with allergic rhinitis. Upper six panels: normal subject (right nasal cavity). Lower six panels: patient with allergic rhinitis (left nasal cavity). The surfaces are smoother and more even in these images, compared with the images from the patient with SARS-CoV-2. The inferior turbinate was paler and smoother in patients with allergic rhinitis than in normal subjects, but the surfaces were similarly uniform. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; HSL, hue, saturation, and luminance.

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