Tuberc Respir Dis.  1969 Sep;16(3):39-44. 10.4046/trd.1969.16.3.39.

Circulating Blood Volume in Various Respiratory Diseases

Abstract

Circulating blood volume was determined utilizing radioactive iodinated human serum albumin in 63 cases with various respiratory conditions, and the results were compared to those of the normal controls. In addition, in pulmonary emphysema and far advanced pulmonary tuberculosis comparison of the results was made between those with and without cor pulmonale. In pleurisy and pneumonia red cell volume showed no significant deviation from that of the normal control but increased total blood volume caused by increased plasma volume was observed. In bronchiectasis and Bronchogenic carcinoma, both red cell and plasma volumes were not significantly different from those of the normal controls, But in lung abscess decrease in red cell and increase in plasma volume were noted. In pulmonary emphysema with cor pulmonale both red cell and plasma volumes were greater than those in the normal controls, whereas only plasma volume was greater in thoes without cor pulmonale, and .in the former red cell volume was greater than in the latter. In minimal .and moderately advanced pulmonary tuberculosis, increase in plasma volume was observed, whereas in far advanced cases with cor pulmonale both red cel.l and total blood volumes were increased, and in those without cor pulmonale both red cell and total blood volumes were increased. It was also noted that red cell volumes was greater in those with cor pulmonale than in those without it.

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