Nucl Med Mol Imaging.  2022 Feb;56(1):59-62. 10.1007/s13139-021-00725-3.

F‑18 FDG PET/CT in NK/T‑Cell Lymphoma that Progressed from Epstein‑Barr Virus‑Associated Hemophagocytic Lymphohistiocytosis

Affiliations
  • 1Department of Nuclear Medicine & Molecular Imaging, Ajou University School of Medicine, Worldcup‑ro 164, Suwon, Kyunggi‑do 16499, Republic of Korea

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome involving an uncontrolled immune response with variable triggers. HLH is rare but highly fatal, even with proper treatment; therefore, early recognition and diagnosis are crucial for management. Although the role of F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/ CT) in HLH is poorly defined, it can provide valuable information on disease status and possible triggers. Herein, we report an F-18 FDG PET/CT study on a case of NK/T-cell lymphoma that progressed from Epstein-Barr virus-associated HLH.

Keyword

F-18 FDG PET/CT; Hemophagocytic lymphohistiocytosis; Epstein-Barr virus; NK/T-cell lymphoma
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