J Korean Diabetes.  2021 Jun;22(2):85-90. 10.4093/jkd.2021.22.2.85.

Recent Perspective of Metformin

  • 1Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea


Metformin has been used clinically more than 60 years in type 2 diabetes as the first-line drug for treatment. Metformin has been prescribed in more than 80% of Korean patients with diabetes. Despite long-term use and wide prescription of metformin in patients with type 2 diabetes, many questions remain. Recent advances have revealed a new mechanism of action and new benefits of metformin. In this article, we review recent advances regarding metformin treatment.


Cardiovascular diseases; Delayed-action preparations; Diabetes mellitus; type 2; Metformin


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